Probiotics and gut microbiota: Mechanistic insights into gut immune homeostasis through TLR pathway regulation

H Kaur, SA Ali - Food & Function, 2022 - pubs.rsc.org
Consumption of probiotics as a useful functional food improves the host's wellbeing, and,
when paired with prebiotics (indigestible dietary fibre/carbohydrate), often benefits the host …

[HTML][HTML] Upstream and downstream regulators of Klotho expression in chronic kidney disease

SS Li, M Sheng, ZY Sun, Y Liang, LX Yu, QF Liu - Metabolism, 2023 - Elsevier
Klotho is a critical protein that protects the kidney. Klotho is severely downregulated in
chronic kidney disease (CKD), and its deficiency is implicated in the pathogenesis and …

On the potential role of the antioxidant couple vitamin E/selenium taken by the oral route in skin and hair health

J Pincemail, S Meziane - Antioxidants, 2022 - mdpi.com
The relationship between oxidative stress and skin aging/disorders is well established.
Many topical and oral antioxidants (vitamins C and E, carotenoids, polyphenols) have been …

Epigenomic and transcriptomic analyses reveal differences between low-grade inflammation and severe exhaustion in LPS-challenged murine monocytes

LB Naler, YP Hsieh, S Geng, Z Zhou, L Li… - Communications …, 2022 - nature.com
Emerging studies suggest that monocytes can be trained by bacterial endotoxin to adopt
distinct memory states ranging from low-grade inflammation to immune exhaustion. While …

Neuroepigenetics of ageing and neurodegeneration-associated dementia: an updated review

FA Mir, A Amanullah, BP Jain, Z Hyderi… - Ageing Research …, 2023 - Elsevier
Gene expression is tremendously altered in the brain during memory acquisition, recall, and
forgetfulness. However, non-genetic factors, including environmental elements, epigenetic …

The Role of Hydrogen Sulfide (H2S) in Epigenetic Regulation of Neurodegenerative Diseases: A Systematic Review

BG Dogaru, C Munteanu - International Journal of Molecular Sciences, 2023 - mdpi.com
This review explores the emerging role of hydrogen sulfide (H2S) in modulating epigenetic
mechanisms involved in neurodegenerative diseases. Accumulating evidence has begun to …

Targeted intervention of natural medicinal active ingredients and traditional Chinese medicine on epigenetic modification: possible strategies for prevention and …

W Wang, H Li, Y Shi, J Zhou, GJ Khan, J Zhu, F Liu… - Phytomedicine, 2024 - Elsevier
Background Atherosclerosis is a deadly consequence of cardiovascular disease and has
very high mortality rate worldwide. The epigenetic modifications can regulate the …

Diabetic retinopathy and cardiovascular disease: a literature review

W Yu, B Yang, S Xu, Y Gao, Y Huang… - … Syndrome and Obesity, 2023 - Taylor & Francis
Diabetic complications can be divided into macrovascular complications such as
cardiovascular disease and cerebrovascular disease and microvascular complications such …

Melatonin and stress tolerance in horticultural crops: Insights into gene regulation, epigenetic modifications, and hormonal interplay

C Kaya, F Ugurlar - Scientia Horticulturae, 2023 - Elsevier
Horticultural crops are crucial for food, nourishment, and economies worldwide, but they
face challenges from biotic and abiotic stressors, impacting productivity and quality. Effective …

New insight in HDACs: Potential therapeutic targets for the treatment of atherosclerosis

Y Luan, H Liu, Y Luan, Y Yang, J Yang… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis (AS) features include progressive hardening and reduced elasticity of
arteries. AS is the leading cause of morbidity and mortality. An increasing amount of …