With the increase in the expectancy of the life span of humans, neurodegenerative diseases
(NDs) have imposed a considerable burden on the family, society, and nation. In defiance of …

Neuroinflammation is defined as an inflammatory response within the brain or spinal cord,
whereas the brain's innate immune system is triggered by various inflammatory challenges …

The incidence of neurological disorders is growing in developed countries together with
increased lifespan. Nowadays, there are still no effective treatments for neurodegenerative …

Tea polyphenols (TP) was investigated in rats for its protective effect on renal
ischemia/reperfusion injury (RIRI). Rats were randomized into groups as follows:(I) sham …

Tissue plasminogen activator (t-PA) is the only FDA-approved drug for acute ischemic stroke
treatment, but its clinical use is limited due to the narrow therapeutic time window and …

Background: Increasing evidence indicates that amyloid β oligomer (AβO) is toxic to neurons
in Alzheimer's disease (AD) brain. The aim of the present study is to evaluate the effects of …

In recent years, neurological diseases including Alzheimer's disease, Parkinson's disease
and stroke are one of the main causes of death in the world. At the same time, the incidence …

Dengue is the most widespread arbovirus infection and poses a serious health and
economic issue in tropical and subtropical countries. Currently no licensed vaccine or …

Alzheimer's disease (AD) is the most common neurodegenerative disease, and its incidence
is increasing worldwide with increased lifespan. Currently, there is no effective treatment to …

The pharmaceutical industry is increasingly joining chemoinformatics in the search for the
development of new drugs to be used in the treatment of diseases. These computational …