MiRNA-based therapies for lung cancer: Opportunities and challenges?
H Yang, Y Liu, L Chen, J Zhao, M Guo, X Zhao, Z Wen… - Biomolecules, 2023 - mdpi.com
Lung cancer is a commonly diagnosed cancer and the leading cause of cancer-related
deaths, posing a serious health risk. Despite new advances in immune checkpoint and …
deaths, posing a serious health risk. Despite new advances in immune checkpoint and …
miR-199a: a tumor suppressor with noncoding rna network and therapeutic candidate in lung cancer
W Meng, Y Li, B Chai, X Liu, Z Ma - International journal of molecular …, 2022 - mdpi.com
Lung cancer is the leading cause of cancer death worldwide. miR-199a, which has two
mature molecules: miR-199a-3p and miR-199a-5p, plays an important biological role in the …
mature molecules: miR-199a-3p and miR-199a-5p, plays an important biological role in the …
Tumor-intrinsic PD-L1 exerts an oncogenic function through the activation of the Wnt/β-catenin pathway in human non-small cell lung cancer
Programmed death ligand 1 (PD-L1) strongly inhibits T cell activation, thereby aiding tumors
in escaping the immune response. PD-L1 inhibitors have proven to be effective in the …
in escaping the immune response. PD-L1 inhibitors have proven to be effective in the …
miR-199a/b-3p inhibits HCC cell proliferation and invasion through a novel compensatory signaling pathway DJ-1\Ras\PI3K/AKT
LN Ma, LN Wu, S Liu, X Zhang, X Luo, S Nawaz… - Scientific Reports, 2024 - nature.com
Several studies have reported the effects of DJ-1 gene and miR-199a/b-3p on HCC
development. However, whether miR-199a/b-3p regulates HCC progression through a …
development. However, whether miR-199a/b-3p regulates HCC progression through a …
miR-199a-3p promotes gastric cancer progression by promoting its stemness potential via DDR2 mediation
L Ren, Q Ren, J Wang, Y He, H Deng, X Wang, C Liu - Cellular Signalling, 2023 - Elsevier
Background Peritoneal metastasis (PM) is an independent prognostic factor in gastric
cancer (GC), however, the underlying mechanisms of PM occurrence remain unclear …
cancer (GC), however, the underlying mechanisms of PM occurrence remain unclear …
[HTML][HTML] Erianin promotes apoptosis and inhibits Akt-mediated aerobic glycolysis of cancer cells
S Han, S Chen, J Wang, S Huang, Y Xiao… - Journal of …, 2024 - ncbi.nlm.nih.gov
Highly activated aerobic glycolysis provides the metabolic requirements for tumor cell
growth and proliferation. Erianin, a natural product isolated from Dendrobium chrysotoxum …
growth and proliferation. Erianin, a natural product isolated from Dendrobium chrysotoxum …
[HTML][HTML] Exosomal hsa-miR-151a-3p and hsa-miR-877-5p are potential novel biomarkers for predicting bone metastasis in lung cancer
K Zhao, C Jia, J Wang, W Shi, X Wang, Y Song… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Exosomal miRNAs (exo-miRNAs) have arisen as novel diagnostic biomarkers for various
cancers. However, few reports on exo-miRNAs related to bone metastasis (BM) in lung …
cancers. However, few reports on exo-miRNAs related to bone metastasis (BM) in lung …
[HTML][HTML] Exploring the roles of non-coding RNAs in liver regeneration
P Li, X Ma, D Huang, X Gu - Non-coding RNA Research, 2024 - Elsevier
Liver regeneration (LR) is a complex process encompassing three distinct phases: priming,
proliferation phase and restoration, all influenced by various regulatory factors. After liver …
proliferation phase and restoration, all influenced by various regulatory factors. After liver …
miR-199a-5p targets DUSP14 to regulate cell proliferation, invasion and stemness in non-small cell lung cancer
Y Zheng, C Yang, S Xie, D Liu, H Wang, J Liu - Heliyon, 2024 - cell.com
Background Non-small cell lung cancer (NSCLC) shows the highest morbidity among
malignant tumors worldwide. Despite improvements of diagnosis and treatment, patient …
malignant tumors worldwide. Despite improvements of diagnosis and treatment, patient …
[HTML][HTML] LncRNA NORAD 通过miR-199a-3p 调控ZNF217 对非小细胞肺癌细胞增殖、 凋亡及化疗敏感性的影响
GAO Ying, LUO Xiaolin, L Pengfei… - Chinese Journal of …, 2023 - ncbi.nlm.nih.gov
背景与目的针对非小细胞肺癌（ non-small cell lung cancer, NSCLC） 的治疗和诊断仍然是医学
界的难题， 而探究NSCLC 发生发展的分子机制是当前研究的热点。 长链非编码RNA（ long non …
界的难题， 而探究NSCLC 发生发展的分子机制是当前研究的热点。 长链非编码RNA（ long non …