[HTML][HTML] Epigenetics across the human lifespan

RR Kanherkar, N Bhatia-Dey, AB Csoka - Frontiers in cell and …, 2014 - frontiersin.org
Epigenetics has the potential to explain various biological phenomena that have heretofore
defied complete explication. This review describes the various types of endogenous human …

Epigenetic mechanisms of drug addiction

EJ Nestler - Neuropharmacology, 2014 - Elsevier
Drug addiction involves potentially life-long behavioral abnormalities that are caused in
vulnerable individuals by repeated exposure to a drug of abuse. The persistence of these …

Protein persulfidation: Rewiring the hydrogen sulfide signaling in cell stress response

B He, Z Zhang, Z Huang, X Duan, Y Wang, J Cao… - Biochemical …, 2023 - Elsevier
The past few decades have witnessed significant progress in the discovery of hydrogen
sulfide (H 2 S) as a ubiquitous gaseous signaling molecule in mammalian physiology, akin …

Escalation of drug self-administration as a hallmark of persistent addiction liability

S Edwards, GF Koob - Behavioural pharmacology, 2013 - journals.lww.com
Drug addiction is a progressive, relapsing disease comprised of interlocking stages of
disordered motivation. Numerous animal models describing various stages of the addiction …

[HTML][HTML] Alcohol and head and neck cancer: updates on the role of oxidative stress, genetic, epigenetics, oral microbiota, antioxidants, and alkylating agents

G Ferraguti, S Terracina, C Petrella, A Greco, A Minni… - Antioxidants, 2022 - mdpi.com
Head and neck cancer (HNC) concerns more than 890,000 patients worldwide annually and
is associated with the advanced stage at presentation and heavy outcomes. Alcohol …

Epigenetic mechanisms of alcoholism and stress-related disorders

M Palmisano, SC Pandey - Alcohol, 2017 - Elsevier
Stress-related disorders, such as anxiety, early life stress, and posttraumatic stress disorder
appear to be important factors in promoting alcoholism, as alcohol consumption can …

Emerging role of epigenetic mechanisms in alcohol addiction

TDM Berkel, SC Pandey - Alcoholism: Clinical and …, 2017 - Wiley Online Library
Alcohol use disorder (AUD) is a complex brain disorder with an array of persistent
behavioral and neurochemical manifestations. Both genetic and environmental factors are …

[HTML][HTML] Alcohol and NMDA receptor: current research and future direction

R Chandrasekar - Frontiers in molecular neuroscience, 2013 - frontiersin.org
The brain is one of the major targets of alcohol actions. Most of the excitatory synaptic
transmission in the central nervous system is mediated by N-methyl-D-aspartate (NMDA) …

How alcohol drinking affects our genes: an epigenetic point of view

S Ciafrè, V Carito, G Ferraguti, A Greco… - … and Cell Biology, 2019 - cdnsciencepub.com
This work highlights recent studies in epigenetic mechanisms that play a role in alcoholism,
which is a complex multifactorial disorder. There is a large body of evidence showing that …

Neurosteroids (allopregnanolone) and alcohol use disorder: from mechanisms to potential pharmacotherapy

E Gatta, D Camussi, J Auta, A Guidotti… - Pharmacology & …, 2022 - Elsevier
Abstract Alcohol Use Disorder (AUD) is a multifaceted relapsing disorder that is commonly
comorbid with psychiatric disorders, including anxiety. Alcohol exposure produces a …