The finding that many drugs that have abuse potential and other natural stimuli such as food
or sexual activity cause similar chemical changes in the brain, an increase in extracellular …

Functional elucidation of the endogenous opioid system temporally paralleled the creation
and growth of the journal, Peptides, under the leadership of its founding editor, Dr. Abba …

Separate groups of food-deprived rats were given 2h access to food after receiving bilateral
nucleus accumbens infusions of the muscarinic antagonist scopolamine methyl bromide (at …

Datura metel L.(D. metel) is one well-known folk medical herb with wide application and also
the most abused plants all over the world, mainly for spiritual or religious purpose, over …

Rats display both conditioned flavor preference (CFP) for fructose, and conditioned flavor
avoidance (CFA) following sweet adulteration with quinine. Previous pharmacological …

Nutritive (eg, sucrose) and non-nutritive (eg, saccharin) sweeteners stimulate intake in
inbred mouse strains. BALB/c, SWR and C57BL/6 mice differ in the ability of dopamine (DA) …

The infants experience withdrawal from opiates, and time-dependent adaptations in
neuronal activity of nucleus accumbens (NAc) may be crucial for this process. A key …

Rationale Intra-striatal infusions of the muscarinic antagonist, scopolamine, markedly
suppress feeding; however, the underlying mechanisms are unclear. Recent findings …

Sibutramine hydrochloride monohydrate is the only centrally active weight-modifying agent
currently approved by the FDA for long-term use in the treatment of obesity. Systemic …

It is well established that opioid systems in the brain exert an important modulatory influence
on food intake. Even before the discovery of the endogenous opioid peptides or the cloning …