The endocannabinoid system and cannabidiol's promise for the treatment of substance use disorder

Y Chye, E Christensen, N Solowij, M Yücel - Frontiers in psychiatry, 2019 - frontiersin.org
Substance use disorder is characterized by repeated use of a substance, leading to
clinically significant distress, making it a serious public health concern. The …

Cannabidiol treatment might promote resilience to cocaine and methamphetamine use disorders: a review of possible mechanisms

C Calpe-López, MP García-Pardo, MA Aguilar - Molecules, 2019 - mdpi.com
Currently, there are no approved pharmacotherapies for addiction to cocaine and other
psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a …

Polydrug use and its association with drug treatment outcomes among primary heroin, methamphetamine, and cocaine users

L Wang, JE Min, E Krebs, E Evans, D Huang… - International Journal of …, 2017 - Elsevier
Background Polydrug use may challenge effective treatment for substance use disorders.
We evaluate whether secondary substance use modifies the association between treatment …

Cannabidiol as a treatment for craving and relapse in individuals with cocaine use disorder: A randomized placebo‐controlled trial

V Mongeau‐Pérusse, S Brissette, J Bruneau… - …, 2021 - Wiley Online Library
ABSTRACT Background and Aims Cocaine use disorder (CUD) is a significant public health
concern for which no efficacious pharmacological interventions are available. Cannabidiol …

Intentional cannabis use to reduce crack cocaine use in a Canadian setting: A longitudinal analysis

ME Socías, T Kerr, E Wood, H Dong, S Lake… - Addictive …, 2017 - Elsevier
Background No effective pharmacotherapies exist for the treatment of crack cocaine use
disorders. Emerging data suggests that cannabinoids may play a role in reducing cocaine …

[HTML][HTML] Evaluation of the potential use of cannabidiol in the treatment of cocaine use disorder: A systematic review

LA Rodrigues, MES Caroba, FK Taba, R Filev… - Pharmacology …, 2020 - Elsevier
Background Cannabinoids may have an important therapeutic potential for the treatment of
dependence on crack cocaine. Cannabidiol (CBD), in particular, has anxiolytic …

Cannabidiol (CBD) reduces cocaine-environment memory in mice

R Chesworth, T Karl - Pharmacology Biochemistry and Behavior, 2020 - Elsevier
Rationale Cocaine addiction is a global health problem with no approved
pharmacotherapies. Preclinical research indicates the non-intoxicating phytocannabinoid …

The association between cocaine product use and violence outcomes in Brazil: A comprehensive, systematized review

D Daldegan-Bueno, B Fischer - Aggression and violent behavior, 2023 - Elsevier
Violence is a major adverse outcome associated with cocaine use. Brazil presents a unique
case study with high levels of cocaine use. We present a systematized, comprehensive …

Evaluation of two commercially available cannabidiol formulations for use in electronic cigarettes

MR Peace, KE Butler, CE Wolf, JL Poklis… - Frontiers in …, 2016 - frontiersin.org
Since 24 states and the District of Columbia have legalized marijuana in some form,
suppliers of legal marijuana have developed Cannabis sativa products for use in electronic …

Prescription psychostimulants for cocaine use disorder: A review from molecular basis to clinical approach

VS Tardelli, LF Berro, G Gerra, L Tadonio… - Addiction …, 2023 - Wiley Online Library
Cocaine use is a public health concern in many countries worldwide, particularly in the
Americas and Oceania. Overdose deaths involving stimulants, such as cocaine, have been …