Molecular mechanism and application of somatic cell cloning in mammals—Past, present and future

M Samiec - International Journal of Molecular Sciences, 2022 - mdpi.com
Thus far, nearly 25 mammalian species have been cloned by intra-or interspecies somatic
cell nuclear transfer (SCNT). Among them, non-transgenic and transgenic representatives of …

[HTML][HTML] Cloning horses by somatic cell nuclear transfer: Effects of oocyte source on development to foaling

JV Cortez, K Hardwicke, J Cuervo-Arango, CG Grupen - Theriogenology, 2023 - Elsevier
The cloning of horses is a commercial reality, yet the availability of oocytes for cloned
embryo production remains a major limitation. Immature oocytes collected from abattoir …

Simultaneous inhibition of histone deacetylases and RNA synthesis enables totipotency reprogramming in pig SCNT embryos

MP de Macedo, WG Glanzner, K Gutierrez… - International Journal of …, 2022 - mdpi.com
Combining somatic cell nuclear transfer (SCNT) with genome editing technologies has
emerged as a powerful platform for the creation of unique swine lineages for agricultural and …

Tetraploid embryo aggregation produces high-quality blastocysts with an increased trophectoderm in pigs

J Lee, L Cai, M Kim, H Choi, D Oh, A Jawad… - Frontiers in Cell and …, 2023 - frontiersin.org
Tetraploid complementation is an ideal method for demonstrating the differentiation potential
of pluripotent stem cells. In this study, we selected the most efficient tetraploid production …

Somatic Cell Nuclear Transfer in Pigs

WG Glanzner, VB Rissi, V Bordignon - Somatic Cell Nuclear Transfer …, 2023 - Springer
Somatic cell nuclear transfer (SCNT) has been successfully applied to clone animals of
several species. Pigs are one of the main livestock species for food production and are also …