[HTML][HTML] Inflammation and cancer: paradoxical roles in tumorigenesis and implications in immunotherapies

X Liu, L Yin, S Shen, Y Hou - Genes & Diseases, 2023 - Elsevier
Chronic inflammation caused by persistent infections and metabolic disorders is thought to
contribute to the increased cancer risk and the accelerated cancer progression. Oppositely …

Emerging role of mitochondria in airborne particulate matter-induced immunotoxicity

J Sharma, K Parsai, P Raghuwanshi, SA Ali… - Environmental …, 2021 - Elsevier
The immune system is one of the primary targets of airborne particulate matter. Recent
evidence suggests that mitochondria lie at the center of particulate matter-induced …

Associations between long-term exposure to PM2. 5 and site-specific cancer mortality: A nationwide study in Brazil between 2010 and 2018

P Yu, R Xu, S Li, MSZS Coelho, PHN Saldiva… - Environmental …, 2022 - Elsevier
Long-term exposure to PM 2.5 has been linked to lung cancer incidence and mortality, but
limited evidence existed for other cancers. This study aimed to assess the association …

[HTML][HTML] Particulate matter induces inflammatory cytokine production via activation of NFκB by TLR5-NOX4-ROS signaling in human skin keratinocyte and mouse skin

YS Ryu, KA Kang, MJ Piao, MJ Ahn, JM Yi, YM Hyun… - Redox biology, 2019 - Elsevier
Particulate matter (PM) increases levels of pro-inflammatory cytokines, but its effects on the
skin remain largely unknown. We investigated the signal transduction pathway and …

[HTML][HTML] Astragaloside IV alleviates PM2. 5-caused lung toxicity by inhibiting inflammasome‐mediated pyroptosis via NLRP3/caspase-1 axis inhibition in mice

D Huang, S Shi, Y Wang, X Wang, Z Shen… - Biomedicine & …, 2022 - Elsevier
Exposure to particulate matter (PM) 2.5 in air pollution is a serious health issue worldwide.
At present, effective prevention measures and modalities of treatment for PM2. 5-caused …

Emerging insights into the impact of air pollution on immune-mediated asthma pathogenesis

JA Tuazon, B Kilburg-Basnyat, LM Oldfield… - Current allergy and …, 2022 - Springer
Abstract Purpose of Review Increases in ambient levels of air pollutants have been linked to
lung inflammation and remodeling, processes that lead to the development and …

[HTML][HTML] iRhom2 loss alleviates renal injury in long-term PM2. 5-exposed mice by suppression of inflammation and oxidative stress

G Chenxu, X Minxuan, Q Yuting, G Tingting, L Jinxiao… - Redox biology, 2018 - Elsevier
Abstract Particulate matter (PM2. 5) is a risk factor for organ injury and disease progression,
such as lung, brain and liver. However, its effects on renal injury and the underlying …

Deciphering the code between air pollution and disease: The effect of particulate matter on cancer hallmarks

M Santibáñez-Andrade, YI Chirino… - International journal of …, 2019 - mdpi.com
Air pollution has been recognized as a global health problem, causing around 7 million
deaths worldwide and representing one of the highest environmental crises that we are now …

Pathogenic role of air pollution particulate matter in cardiometabolic disease: evidence from mice and humans

T Marchini, A Zirlik, D Wolf - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: Air pollution is a considerable global threat to human health that dramatically
increases the risk for cardiovascular pathologies, such as atherosclerosis, myocardial …

[HTML][HTML] Impacts of air pollution, temperature, and relative humidity on leukocyte distribution: an epigenetic perspective

XU Gao, E Colicino, J Shen, MA Kioumourtzoglou… - Environment …, 2019 - Elsevier
Background Exploring the associations of air pollution and weather variables with blood
leukocyte distribution is critical to understand the impacts of environmental exposures on the …