Air-Liquid interface cultures to model drug delivery through the mucociliary epithelial barrier
RE Lee, B Reidel, MR Nelson, JK Macdonald… - Advanced Drug Delivery …, 2023 - Elsevier
Epithelial cells from mucociliary portions of the airways can be readily grown and expanded
in vitro. When grown on a porous membrane at an air–liquid interface (ALI) the cells form a …
in vitro. When grown on a porous membrane at an air–liquid interface (ALI) the cells form a …
Microfluidic chip as a promising evaluation method in assisted reproduction: A systematic review
T Wu, Y Wu, J Yan, J Zhang… - … & Translational Medicine, 2024 - Wiley Online Library
The aim of assisted reproductive technology (ART) is to select the high‐quality sperm,
oocytes, and embryos, and finally achieve a successful pregnancy. However, functional …
oocytes, and embryos, and finally achieve a successful pregnancy. However, functional …
Material properties of nonpregnant and pregnant human uterine layers
The uterus has critical biomechanical functions in pregnancy and undergoes dramatic
material growth and remodeling from implantation to parturition. The intrinsic material …
material growth and remodeling from implantation to parturition. The intrinsic material …
Report of the assay guidance workshop on 3-dimensional tissue models for antiviral drug development
R Jordan, SL Ford-Scheimer… - The Journal of …, 2023 - academic.oup.com
Abstract The National Center for Advancing Translational Sciences (NCATS) Assay
Guidance Manual (AGM) Workshop on 3D Tissue Models for Antiviral Drug Development …
Guidance Manual (AGM) Workshop on 3D Tissue Models for Antiviral Drug Development …
Advanced Technologies for Studying Microbiome–Female Reproductive Tract Interactions: Organoids, Organoids-on-a-Chip, and Beyond
YA Kaya, MR de Zoete, GS Steba - Seminars in reproductive …, 2024 - thieme-connect.com
The female reproductive tract (FRT) is home to diverse microbial communities that play a
pivotal role in reproductive health and disorders such as infertility, endometriosis, and …
pivotal role in reproductive health and disorders such as infertility, endometriosis, and …
[HTML][HTML] Notoginsenoside R1 promotes Lgr5+ stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling
Z Yu, R Gao, C Lv, X Geng, Y Ren, J Zhang… - Acta Pharmacologica …, 2024 - nature.com
Inflammatory bowel disease (IBD) is characterized by persistent damage to the intestinal
barrier and excessive inflammation, leading to increased intestinal permeability. Current …
barrier and excessive inflammation, leading to increased intestinal permeability. Current …
[HTML][HTML] Hydrogel-Integrated Millifluidic Systems: Advancing the Fabrication of Mucus-Producing Human Intestinal Models
A Almalla, N Alzain, L Elomaa, F Richter, J Scholz… - Cells, 2024 - mdpi.com
The luminal surface of the intestinal epithelium is protected by a vital mucus layer, which is
essential for lubrication, hydration, and fostering symbiotic bacterial relationships …
essential for lubrication, hydration, and fostering symbiotic bacterial relationships …
Mucus‐Mimicking Mucin‐Based Hydrogels by Tandem Chemical and Physical Crosslinking
NN Porfiryeva, I Zlotver… - Macromolecular …, 2024 - Wiley Online Library
Mucosal tissues represent a major interface between the body and the external environment
and are covered by a highly hydrated mucins gel called mucus. Mucus lubricates, protects …
and are covered by a highly hydrated mucins gel called mucus. Mucus lubricates, protects …
Tumour organoids and assembloids: Patient‐derived cancer avatars for immunotherapy
J Mei, X Liu, HX Tian, Y Chen, Y Cao… - Clinical and …, 2024 - Wiley Online Library
Background Organoid technology is an emerging and rapidly growing field that shows
promise in studying organ development and screening therapeutic regimens. Although …
promise in studying organ development and screening therapeutic regimens. Although …
[HTML][HTML] Advances in the Evaluation of Gastrointestinal Absorption Considering the Mucus Layer
K Miyazaki, A Sasaki, H Mizuuchi - Pharmaceutics, 2023 - mdpi.com
Because of the increasing sophistication of formulation technology and the increasing
polymerization of compounds directed toward undruggable drug targets, the influence of the …
polymerization of compounds directed toward undruggable drug targets, the influence of the …