Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

N Kamaly, Z Xiao, PM Valencia… - Chemical Society …, 2012 - pubs.rsc.org
Polymeric materials have been used in a range of pharmaceutical and biotechnology
products for more than 40 years. These materials have evolved from their earlier use as …

[HTML][HTML] Prospective of 68Ga-radiopharmaceutical development

I Velikyan - Theranostics, 2014 - ncbi.nlm.nih.gov
Abstract Positron Emission Tomography (PET) experienced accelerated development and
has become an established method for medical research and clinical routine diagnostics on …

Clinical applications of Gallium-68

SR Banerjee, MG Pomper - Applied Radiation and Isotopes, 2013 - Elsevier
Gallium-68 is a positron-emitting radioisotope that is produced from a 68Ge/68Ga generator.
As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron …

Diagnostic performance of Gallium-68 somatostatin receptor PET and PET/CT in patients with thoracic and gastroenteropancreatic neuroendocrine tumours: a meta …

G Treglia, P Castaldi, G Rindi, A Giordano, V Rufini - Endocrine, 2012 - Springer
Abstract Gallium-68 somatostatin receptor (SMSR) positron emission tomography (PET) and
positron emission tomography/computed tomography (PET/CT) are valuable diagnostic …

Small targeted cytotoxics: current state and promises from DNA‐encoded chemical libraries

N Krall, J Scheuermann, D Neri - … Chemie International Edition, 2013 - Wiley Online Library
The targeted delivery of potent cytotoxic agents has emerged as a promising strategy for the
treatment of cancer and other serious conditions. Traditionally, antibodies against markers of …

[HTML][HTML] Neurotheranostics as personalized medicines

BD Kevadiya, BM Ottemann, MB Thomas… - Advanced Drug Delivery …, 2019 - Elsevier
The discipline of neurotheranostics was forged to improve diagnostic and therapeutic
clinical outcomes for neurological disorders. Research was facilitated, in largest measure …

Targeted radionuclide therapy: an evolution toward precision cancer treatment

H Jadvar - American Journal of Roentgenology, 2017 - Am Roentgen Ray Soc
OBJECTIVE. This article reviews recent developments in targeted radionuclide therapy
(TRT) approaches directed to malignant liver lesions, bone metastases, neuroendocrine …

Peptide receptor targeting in cancer: the somatostatin paradigm

F Barbieri, A Bajetto, A Pattarozzi… - … journal of peptides, 2013 - Wiley Online Library
Peptide receptors involved in pathophysiological processes represent promising therapeutic
targets. Neuropeptide somatostatin (SST) is produced by specialized cells in a large number …

Synthesis of peptide radiopharmaceuticals for the therapy and diagnosis of tumor diseases

M Jamous, U Haberkorn, W Mier - Molecules, 2013 - mdpi.com
Despite the advances in molecular biology and biochemistry, the prognosis of patients
suffering from tumor diseases remains poor. The limited therapeutic success can be …

225Ac-Labeled Somatostatin Analogs in the Management of Neuroendocrine Tumors: From Radiochemistry to Clinic

L Rubira, E Deshayes, L Santoro, PO Kotzki, C Fersing - Pharmaceutics, 2023 - mdpi.com
The widespread use of peptide receptor radionuclide therapy (PRRT) represents a major
therapeutic breakthrough in nuclear medicine, particularly since the introduction of 177Lu …