[HTML][HTML] Global and regional prevalence of vitamin D deficiency in population-based studies from 2000 to 2022: A pooled analysis of 7.9 million participants

A Cui, T Zhang, P Xiao, Z Fan, H Wang… - Frontiers in Nutrition, 2023 - frontiersin.org
Background Vitamin D deficiency causes the bone hypomineralization disorder
osteomalacia in humans and is associated with many non-skeletal disorders. We aim to …

[HTML][HTML] Guidelines for preventing and treating vitamin D deficiency: a 2023 update in Poland

P Płudowski, B Kos-Kudła, M Walczak, A Fal… - Nutrients, 2023 - mdpi.com
Introduction: All epidemiological studies suggest that vitamin D deficiency is prevalent
among the Polish general population. Since vitamin D deficiency was shown to be among …

[HTML][HTML] Critical appraisal of large vitamin D randomized controlled trials

S Pilz, C Trummer, V Theiler-Schwetz, MR Grübler… - Nutrients, 2022 - mdpi.com
As a consequence of epidemiological studies showing significant associations of vitamin D
deficiency with a variety of adverse extra-skeletal clinical outcomes including cardiovascular …

Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study

A Zhou, E Hyppönen - International Journal of Epidemiology, 2023 - academic.oup.com
Background Low vitamin D status is often associated with systemic low-grade inflammation
as reflected by elevated C-reactive protein (CRP) levels. We investigated the causality and …

[HTML][HTML] Comparing the evidence from observational studies and randomized controlled trials for nonskeletal health effects of vitamin D

WB Grant, BJ Boucher, F Al Anouti, S Pilz - Nutrients, 2022 - mdpi.com
Although observational studies of health outcomes generally suggest beneficial effects with,
or following, higher serum 25-hydroxyvitamin D [25 (OH) D] concentrations, randomized …

[HTML][HTML] Non-linear mendelian randomization: detection of biases using negative controls with a focus on BMI, vitamin D and ldl cholesterol

FW Hamilton, DA Hughes, W Spiller, K Tilling… - European Journal of …, 2024 - Springer
Mendelian randomisation (MR) is an established technique in epidemiological investigation,
using the principle of random allocation of genetic variants at conception to estimate the …

[HTML][HTML] A narrative review of the evidence for variations in serum 25-hydroxyvitamin D concentration thresholds for optimal health

WB Grant, F Al Anouti, BJ Boucher, E Dursun… - Nutrients, 2022 - mdpi.com
Vitamin D3 has many important health benefits. Unfortunately, these benefits are not widely
known among health care personnel and the general public. As a result, most of the world's …

[HTML][HTML] Dietary recommendations for post-COVID-19 syndrome

L Barrea, WB Grant, E Frias-Toral, C Vetrani, L Verde… - Nutrients, 2022 - mdpi.com
At the beginning of the coronavirus disease (COVID-19) pandemic, global efforts focused on
containing the spread of the virus and avoiding contagion. Currently, it is evident that health …

[HTML][HTML] Vitamin D as a Shield against Aging

C Fantini, C Corinaldesi, A Lenzi, S Migliaccio… - International Journal of …, 2023 - mdpi.com
Aging can be seen as a physiological progression of biomolecular damage and the
accumulation of defective cellular components, which trigger and amplify the process …

Health effects of vitamin D supplementation: lessons learned from randomized controlled trials and mendelian randomization studies

R Bouillon, MS LeBoff, RE Neale - Journal of Bone and Mineral …, 2023 - academic.oup.com
Vitamin D plays an important role in calcium homeostasis and many cellular processes.
Although vitamin D supplements are widely recommended for community‐dwelling adults …