Implantation is the first step in human reproduction. Successful implantation depends on the
crosstalk between embryo and endometrium. Recurrent implantation failure (RIF) is a …

The aim of the present systematic review and meta-analysis was to assess the effect of the
different therapeutic options for repeated embryo implantation failure (RIF) on a subsequent …

Importance To date, recurrent implantation failure (RIF) has no clear definition and no clearly
identified impaired function. Hence, the term RIF is currently used somewhat haphazardly …

Repeated implantation failures are a constant challenge in reproductive medicine with a
significant impact both on health providers and on infertile couples. Several approaches …

As co-stimulatory receptors, immune checkpoint molecules are found on the surface of
various immune cells and transduce inhibitory signals following ligand binding. The most …

In brief Immune dysfunction may contribute to or cause recurrent implantation failure. This
article summarizes normal and pathologic immune responses at implantation and critically …

BACKGROUND There is a wealth of information regarding interventions for treating
subfertility. The majority of studies exploring interventions for improving conception rates …

Maternal-fetal immune dysregulation is one of the risk factors that increases the probability
of embryo rejection and reproductive failure. The stimulation of immunological tolerance and …

Embryo implantation in the uterus is an essential process for successful pregnancy in
mammals. In general, the endocrine system induces sufficient embryo receptivity in the …

This meta-analysis analyzed the clinical pregnancy outcomes of repeated implantation
failure (RIF) patients treated with immunomodulatory therapies. Publications (published by …