Epithelial-mesenchymal transition (EMT) is a cellular process by which epithelial cells lose
their characteristics and acquire mesenchymal traits to promote cell movement. This …

Cellular plasticity lies at the core of cancer progression, metastasis, and resistance to
treatment. Stemness and epithelial-mesenchymal plasticity in cancer are concepts that …

Cancer cells feature a resting membrane potential (V m) that is depolarized compared to
normal cells, and express active ionic conductances, which factor directly in their …

Prostate cancer (PCa) is a complex disease. An ongoing accumulation of mutations results
in increased genetic diversity, with the tumor acquiring distinct subclones. However, non …

Cellular plasticity is a well-recognized dynamic characteristic of tumor cells, which endows
tumors with heterogeneity and therapy resistance, and alters their invasion-metastasis …

Immune evasion and metabolic reprogramming are hallmarks of cancer progression often
associated with a poor prognosis and frequently present significant challenges for cancer …

Despite advancements in cancer management, tumor relapse and metastasis are
associated with poor outcomes in many cancers. Over the past decade, oncogene-driven …

The epithelial-mesenchymal transition (EMT) is a vital driver of tumor progression. It is a well-
known and complex trans-differentiation process in which epithelial cells undergo …

Epithelial-mesenchymal plasticity (EMP) refers to the ability of cells to dynamically
interconvert between epithelial (E) and mesenchymal (M) phenotypes, thus generating an …

Growth and metastasis of colorectal cancer is closely connected to the biosynthetic capacity
of tumor cells, and colorectal cancer stem cells that reside at the top of the intratumoral …