Molecular regulation of the key specialized metabolism pathways in medicinal plants

M Shi, S Zhang, Z Zheng, I Maoz… - Journal of Integrative …, 2024 - Wiley Online Library
The basis of modern pharmacology is the human ability to exploit the production of
specialized metabolites from medical plants, for example, terpenoids, alkaloids, and …

Engineering the plant metabolic system by exploiting metabolic regulation

S Selma, N Ntelkis, TH Nguyen… - The Plant …, 2023 - Wiley Online Library
Plants are the most sophisticated biofactories and sources of food and biofuels present in
nature. By engineering plant metabolism, the production of desired compounds can be …

The transcription factor CsS40 negatively regulates TCS1 expression and caffeine biosynthesis in connection to leaf senescence in Camellia sinensis

X Yao, H Chen, A Ai, F Wang, S Lian… - Horticulture …, 2023 - academic.oup.com
Caffeine is considered as one of the most important bioactive components in the popular
plant beverages tea, cacao, and coffee, but as a wide-spread plant secondary metabolite its …

Integrated transcriptomic and metabolomic analysis reveals the molecular basis of tissue-specific accumulation of bioactive steroidal alkaloids in Fritillaria …

H Liao, H Quan, B Huang, H Ji, T Zhang, J Chen… - Phytochemistry, 2023 - Elsevier
Fritillaria unibracteata is an endangered medicinal plant whose bulb has been used as a
Chinese herb to suppress cough, asthma and excessive phlegm for centuries. Steroidal …

Transcriptomic analysis of genes related to alkaloid biosynthesis and the regulation mechanism under precursor and methyl jasmonate treatment in Dendrobium …

C Jiao, M Wei, H Fan, C Song, Z Wang… - Frontiers in Plant …, 2022 - frontiersin.org
Dendrobium officinale is both a traditional herbal medicine and a plant of high ornamental
and medicinal value. Alkaloids, especially terpenoid indole alkaloids (TIAs), with …

Lycium RIN negatively modulate the biosynthesis of kukoamine A in hairy roots through decreasing thermospermine synthase expression

J Wei, AA Chahel, Y Ni, X Wei, Y Zhao, Y Wang… - International Journal of …, 2023 - Elsevier
Root bark (Lycii cortex) of Lycium contains high contents of characteristic bioactive
compounds, including kukoamine A (KuA) and kukoamine B (KuB). RIPENING INHIBITOR …

Comprehensive transcriptomic meta-analysis unveils new responsive genes to methyl jasmonate and ethylene in Catharanthus roseus

SN Tabatabaeipour, B Shiran, R Ravash, A Niazi… - Heliyon, 2024 - cell.com
In Catharanthus roseus, vital plant hormones, namely methyl jasmonate (MeJA) and
ethylene, serve as abiotic triggers, playing a crucial role in stimulating the production of …

California poppy (Eschscholzia californica), the Papaveraceae golden girl model organism for evodevo and specialized metabolism

A Becker, Y Yamada, F Sato - Frontiers in plant science, 2023 - frontiersin.org
California poppy or golden poppy (Eschscholzia californica) is the iconic state flower of
California, with native ranges from Northern California to Southwestern Mexico. It grows well …

Clustered regularly interspaced short palindromic repeats tools for plant metabolic engineering: achievements and perspectives

S Selma, E Ceulemans, A Goossens… - Current Opinion in …, 2023 - Elsevier
Highlights•Plant metabolic engineering can boost resilience and nutraceutical value of
crops.•CRISPR tools are used to enhance productivity and specificity of metabolic …

Advances in regulatory mechanism (s) and biotechnological approaches to modulate nicotine content in tobacco

S Dwivedi, D Singh, N Singh, PK Trivedi - Plant Physiology and …, 2024 - Elsevier
More than 8 million deaths are caused by tobacco-related diseases every year. A staggering
1.2 million of those fatalities occur due to second-hand smoke exposure among non …