The nucleocapsid phosphoprotein of the severe acute respiratory syndrome coronavirus
(SARS-CoV N protein) packages the viral genome into a helical ribonucleocapsid (RNP) …

Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …

Electrostatics plays a fundamental role in virtually all processes involving biomolecules in
solution. The Poisson–Boltzmann equation constitutes one of the most fundamental …

The double-stranded RNA binding domain (dsRBD) is a small protein domain of 65–70
amino acids adopting an αβββα fold, whose central property is to bind to double-stranded …

A detailed computational analysis of 32 protein–RNA complexes is presented. A number of
physical and chemical properties of the intermolecular interfaces are calculated and …

Abstract BindN (http://bioinformatics. ksu. edu/bindn/) takes an amino acid sequence as
input and predicts potential DNA or RNA-binding residues with support vector machines …

Sequence-derived structural and physicochemical features have frequently been used in the
development of statistical learning models for predicting proteins and peptides of different …

The severe acute respiratory syndrome (SARS) virus belongs to the Coronaviridea family of
viruses. Its virion encodes several proteins including a replicase and four structural proteins …

Iron regulatory protein 1 (IRP1) binds iron-responsive elements (IREs) in messenger RNAs
(mRNAs), to repress translation or degradation, or binds an iron-sulfur cluster, to become a …