Cadmium, organ toxicity and therapeutic approaches: a review on brain, kidney and testis damage

M Rinaldi, A Micali, H Marini, EB Adamo… - Current medicinal …, 2017 - ingentaconnect.com
Background: Cadmium (Cd) is a heavy metal particularly hazardous for human health, as it
is highly diffused and, therefore, a ubiquitous environmental toxicant. In fact, in the general …

Nutraceuticals: a new challenge against cadmium-induced testicular injury

HR Marini, A Micali, G Squadrito, D Puzzolo, J Freni… - Nutrients, 2022 - mdpi.com
Cadmium (Cd) is a widespread heavy metal and a ubiquitous environmental toxicant. For
the general population, the principal causes of Cd exposure are cigarette smoking, air …

Selenium alleviates cadmium-induced oxidative stress, endoplasmic reticulum stress and programmed necrosis in chicken testes

M Wang, Y Wang, S Wang, L Hou, Z Cui, Q Li… - Science of The Total …, 2023 - Elsevier
Cadmium (Cd) is a common heavy metal pollutant, and one of the important target organs of
its toxicity is the testis. Selenium (Se) has the ability to antagonize the toxicity of Cd …

Anthocyanins from Lycium ruthenicum Murray Mitigate Cadmium-Induced Oxidative Stress and Testicular Toxicity by Activating the Keap1/Nrf2 Signaling Pathway

M Dong, J Lu, H Xue, Y Lou, S Li, T Liu, Z Ding… - Pharmaceuticals, 2024 - mdpi.com
Cadmium (Cd) is a hazardous heavy metal environmental pollutant that has carcinogenic,
teratogenic, and mutagenic properties. Excessive exposure to Cd can induce oxidative …

Subacute testicular toxicity to cadmium exposure intraperitoneally and orally

VGS Mouro, ALP Martins, J Silva… - Oxidative medicine …, 2019 - Wiley Online Library
The toxic effects of cadmium (Cd) on reproductive parameters are widely described in the
literature. Experimental models often make use of the intraperitoneal route (ip), although …

Combined apocynin and carvedilol protect against cadmium-induced testicular damage via modulation of inflammatory response and redox-sensitive pathways

AG Bakr, EHM Hassanein, FEM Ali, EAM El-Shoura - Life Sciences, 2022 - Elsevier
Testicular damage is considered a severe complication of cadmium (Cd) exposure which is
associated with tissue oxidative stress damage, inflammation, and apoptosis. The present …

Purslane (Portulacae oleracea L.) attenuates cadmium-induced hepatorenal and colonic damage in mice: Role of chelation, antioxidant and intestinal microecological …

X Tian, Y Ding, Y Kong, G Wang, S Wang, D Cheng - Phytomedicine, 2021 - Elsevier
Abstract Background Cadmium (Cd) is a representative pernicious metal, which has high
biological toxicity. Its precaution through dietary administration is considered an important …

[HTML][HTML] Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways

YP Jiang, JM Yang, RJ Ye, N Liu, WJ Zhang… - Biomedicine & …, 2019 - Elsevier
Background Blood-testis barrier (BTB) impairments is one of the major secondary
complications of diabetes. Betaine (BET) is the important active ingredients isolated from …

A flavonoid-rich extract from bergamot juice, alone or in association with curcumin and resveratrol, shows protective effects in a murine model of cadmium-induced …

N Ferlazzo, A Micali, HR Marini, J Freni, G Santoro… - Pharmaceuticals, 2021 - mdpi.com
It is known that cadmium damages testis structure and functionality. We examined the effects
of nutraceuticals such as a flavonoid-rich extract of bergamot juice (BJe), alone or in …

Deoxynivalenol induced spermatogenesis disorder by blood-testis barrier disruption associated with testosterone deficiency and inflammation in mice

Z Cao, W Huang, Y Sun, Y Li - Environmental pollution, 2020 - Elsevier
Deoxynivalenol (DON) is an unavoidable cereal crops contaminants and environmental
pollutants, which seriously threated the health of human and animal. DON has been …