Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease characterized by
autoimmune destruction of small to medium size intrahepatic bile ducts. The etiology of PBC …

The liver is a site at which apoptotic CD8+ cells accumulate during the clearance phase of
peripheral immune responses. Normal mouse liver contains an unusual mixture of …

In the last 15 years, the intrahepatic biliary tree has become the object of extensive studies,
which highlighted the extraordinary biologic properties of cholangiocytes involved in bile …

The hepatic stellate cell (HSC), following a fibrogenic stimulus, is transformed from a
quiescent to an activated cell. HSC activation results in numerous changes in cellular …

Neutrophil-induced liver injury during endotoxemia is dependent on the adhesion molecule
Mac-1 (CD11b/CD18) on neutrophils. The potential involvement of its counterreceptor …

Immunologic injury in the liver involves immigrant T and B lymphocytes and a resident
lymphoid population that comprises distinct lymphocytic cells and accessory cells. The …

Abstract Interferon‐γ (IFN‐γ) induces cell‐cycle arrest and p53‐independent apoptosis in
primary cultured hepatocytes. However, the detailed mechanism, including regulating …

Cholangiocytes, or bile duct epithelia, were once thought to be the simple lining of the
conduit system comprising the intra-and extrahepatic bile ducts. Growing experimental …

The hepatic stellate cell (HSC), after a fibrogenic stimulus, is transformed from a quiescent to
an activated phenotype, including the induction of responsiveness to a variety of agonists …

Jaeschke, Hartmut. Cellular adhesion molecules: regulation and functional significance in
the pathogenesis of liver diseases. Am. J. Physiol. 273 (Gastrointest. Liver Physiol. 36) …