Recent research on flavonoids and their biomedical applications

K Wen, X Fang, J Yang, Y Yao… - Current Medicinal …, 2021 - ingentaconnect.com
Flavonoids, commonly found in various plants, are a class of polyphenolic compounds
having a basic structural unit of 2-phenylchromone. Flavonoid compounds have attracted …

Quinoa secondary metabolites and their biological activities or functions

M Lin, P Han, Y Li, W Wang, D Lai, L Zhou - Molecules, 2019 - mdpi.com
Quinoa (Chenopodium quinoa Willd.) was known as the “golden grain” by the native
Andean people in South America, and has been a source of valuable food over thousands …

[HTML][HTML] Pharmacological mechanism of natural drugs and their active ingredients in the treatment of arrhythmia via calcium channel regulation

X Zhang, Y Gao, Y Zhou, Z Liu, R Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Arrhythmia is characterized by abnormal heartbeat rhythms and frequencies caused by
heart pacing and conduction dysfunction. Arrhythmia is the leading cause of death in …

Roles of flavonoids in ischemic heart disease: Cardioprotective effects and mechanisms against myocardial ischemia and reperfusion injury

H Xu, S Yu, C Lin, D Dong, J Xiao, Y Ye, M Wang - Phytomedicine, 2024 - Elsevier
Background Flavonoids are extensively present in fruits, vegetables, grains, and medicinal
plants. Myocardial ischemia and reperfusion (MI/R) comprise a sequence of detrimental …

Natural products as the calcium channel blockers for the treatment of arrhythmia: Advance and prospect

L Xiao, XJ Chen, JK Feng, WN Li, S Yuan, Y Hu - Fitoterapia, 2023 - Elsevier
Arrhythmia is one of the commonly heart diseases with observed abnormal heart-beat
rhythm that caused by the obstacles of cardiac activity and conduction. The arrhythmic …

Aspalathus linearis (Rooibos)–a functional food targeting cardiovascular disease

C Smith, A Swart - Food & function, 2018 - pubs.rsc.org
Increasing consumer bias toward natural products and the considerable wealth of
indigenous knowledge has precipitated an upturn in market-driven research into potentially …

[HTML][HTML] Melatonin protected against myocardial infarction injury in rats through a Sirt6-dependent antioxidant pathway

Y Wang, S Zhang, Y Ma, A Xiang… - … in Clinical and …, 2022 - advances.umw.edu.pl
Background. The Sirt6, one of t he members of the sirtuin family, has been regarded as a key
factor in the pathogenesis of myocardial infarction (MI) through its antioxidant defense …

Orientin suppresses oxidized low-density lipoproteins induced inflammation and oxidative stress of macrophages in atherosclerosis

C Li, C Cai, X Zheng, J Sun, L Ye - Bioscience, Biotechnology …, 2020 - academic.oup.com
Atherosclerosis is a main reason for peripheral vascular disease. The present study aims to
investigate the effects of macrophage foam cells which is an initial part in atherosclerosis …

Orientin Prolongs the Longevity of Caenorhabditis elegans and Postpones the Development of Neurodegenerative Diseases via Nutrition Sensing and Cellular …

Y Qu, L Shi, Y Liu, L Huang, HR Luo… - Oxidative Medicine and …, 2022 - Wiley Online Library
Age is the major risk factor for most of the deadliest diseases. Developing small molecule
drugs with antiaging effects could improve the health of aged people and retard the onset …

Cathelicidin-WA ameliorates diabetic cardiomyopathy by inhibiting the NLRP3 inflammasome

M Peng, Y Liu, Y Xu, L Li, Y Li, H Yang - Cell Cycle, 2021 - Taylor & Francis
Cathelicidin-WA (CWA) is a novel cathelicidin peptide isolated from snakes that has been
suggested to exert anti-inflammatory effects. The aim of our study was to investigate whether …