Identification of a Novel Peptide with Alcohol Dehydrogenase Activating Ability from Ethanol-Induced Lactococcus lactis: A Combined In Silico Prediction and In Vivo …

S Chen, J Yi, Q Kang, M Song… - Journal of Agricultural …, 2024 - ACS Publications
Alcohol dehydrogenase (ADH) is a crucial rate-limiting enzyme in alcohol metabolism. Our
previous research found that ethanol-induced intracellular extracts of Lactococcus lactis (L …

Exploring the therapeutic potential of rutin through investigating its inhibitory mechanism on lactate dehydrogenase: Multi-spectral methods and computer simulation

P Ding, K Yang, H Wang, L Kuang, L Gao, J Luo… - Bioorganic …, 2024 - Elsevier
Lactate dehydrogenase (LDH), a crucial enzyme in anaerobic glycolysis, plays a pivotal role
in the energy metabolism of tumor cells, positioning it as a promising target for tumor …

[HTML][HTML] Kaempferol and nicotiflorin ameliorated alcohol-induced liver injury in mice by miR-138-5p/SIRT1/FXR and gut microbiota

J Ge, G Li, Z Chen, W Xu, X Lei, S Zhu - Heliyon, 2024 - cell.com
Aims Excessive alcohol consumption can lead to alcoholic liver diseases (ALDs).
Tetrastigma hemsleyanum Diels et Gilg is a rare Chinese medicinal herb. Tetrastigma …

Insight into the binding characteristics of epigallocatechin-3-O-gallate and alcohol dehydrogenase: Based on the spectroscopic and molecular docking analysis

X Zhang, L Liu, Y Wang, Y Yu, W Cheng, B Xu… - Spectrochimica Acta Part …, 2024 - Elsevier
Alcohol dehydrogenase (ADH) is one of the pivotal enzymes for alcohol metabolism, which
plays an important role in many physiological processes. In this study, the activation effects …

Comprehensive insights into the binding of crystal violet and pepsin: Spectroscopic analysis, molecular model and biochemical method

Z Xiong, P Ding, C Chen, L Dai, H Zhou, R Cai… - Journal of Molecular …, 2023 - Elsevier
As a well-known triphenylmethane dye, crystal violet (CV) has received extensive concerns
owing to its harmful influence on human health. Pepsin is a digestive enzyme in the stomach …

Unraveling the binding behavior of the antifouling biocide 4, 5-dichloro-2-n-octyl-4-isothiazolin-3-one with human serum albumin: Multi-spectroscopic, atomic force …

J Zhou, J Li, C Cheng, YJ Yao, Y Li, H Liu… - International Journal of …, 2024 - Elsevier
As a marine antifouling biocide, 4, 5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT)
exhibited high toxicity to marine organisms. This study investigated the interaction between …

Multispectral method combined with molecular modelling to investigate the binding mechanisms of DBP and DIBP on pepsin

L Ma, Y Wu, J Zhou, C Cheng, Y Li, Y Yao… - Journal of Molecular …, 2023 - Elsevier
The binding mechanisms of dibutyl phthalate (DBP) and diisobutyl phthalate (DIBP) with
pepsin (PEP) were investigated by multispectral method and computational techniques …

Typical endocrine disruptors diethylstilbestrol and its analogues non-covalently bind to human serum albumin

YS Ao, YM Liu, Y Chen, MM Yin, X Ding… - Journal of Molecular …, 2024 - Elsevier
Endocrine disruptors have received widespread attention from the scientific community.
However, the structure-activity relationship of the binding between endocrine disruptors and …

[HTML][HTML] FtbZIP85 Is Involved in the Accumulation of Proanthocyanidin by Regulating the Transcription of FtDFR in Tartary Buckwheat

S Liu, J Wang, Z Liu, Y Yang, X Li - Current Issues in Molecular Biology, 2023 - mdpi.com
As a drought-tolerant crop, Tartary buckwheat survives under adverse environmental
conditions, including drought stress. Proanthocyanidins (PAs) and anthocyanins are …

Insights into the interaction of cyclooxygenase and lipoxygenase with natural compound 3, 4′, 5, 7-Tetrahydroxyflavone based on multi-spectroscopic and …

J Yi, H Che, J Ren, H Yu, K Song, X Wang… - … Acta Part A: Molecular …, 2023 - Elsevier
Hypoxia induce right ventricular dysfunction in human heart, but the molecular mechanism
remains limited. As known, cyclooxygenases (COX) and lipoxygenases (LOX) play a key …