The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide
consideration because of their immense potential for immunomodulation and their …

Over the past decade, melanoma has led the field in new cancer treatments, with impressive
gains in on-treatment survival but more modest improvements in overall survival. Melanoma …

Cell differentiation and function are regulated across multiple layers of gene regulation,
including modulation of gene expression by changes in chromatin accessibility. However …

Abstract 3D-printed orthopaedic devices and surgical tools, printed maxillofacial implants
and other printed acellular devices have been used in patients. By contrast, bioprinted living …

The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

The cancer stem cell (CSC) concept was proposed four decades ago, and states that tumor
growth, analogous to the renewal of healthy tissues, is fueled by small numbers of dedicated …

Trophoblast cells play an essential role in the interactions between the fetus and mother.
Mouse trophoblast stem (TS) cells have been derived and used as the best in vitro model for …

Alveoli, the lung's respiratory units, are tiny sacs where oxygen enters the bloodstream. They
are lined by flat alveolar type 1 (AT1) cells, which mediate gas exchange, and AT2 cells …

Barrier epithelia depend upon resident stem cells for homeostasis, defense, and repair.
Epithelial stem cells of small and large intestines (ISCs) respond to their local …

The skin barrier is the body's first line of defence against environmental assaults, and is
maintained by epithelial stem cells (EpSCs). Despite the vulnerability of EpSCs to …