4, 4′-Diaminodiphenyl sulfone (DDS) as an inflammasome competitor

J Lee, HK An, MG Sohn, P Kivela, S Oh - International journal of …, 2020 - mdpi.com
The aim of this study is to examine the use of an inflammasome competitor as a preventative
agent. Coronaviruses have zoonotic potential due to the adaptability of their S protein to …

Interleukin‐1 as a common denominator from autoinflammatory to autoimmune disorders: premises, perils, and perspectives

G Lopalco, L Cantarini, A Vitale… - Mediators of …, 2015 - Wiley Online Library
A complex web of dynamic relationships between innate and adaptive immunity is now
evident for many autoinflammatory and autoimmune disorders, the first deriving from …

Immunology in clinic review series; focus on autoinflammatory diseases: update on monogenic autoinflammatory diseases: the role of interleukin (IL)-1 and an …

R Goldbach-Mansky - Clinical & Experimental Immunology, 2012 - academic.oup.com
Summary OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW
SERIES Allergy, Host Responses, Cancer, Type 1 diabetes and viruses, Metabolic diseases …

Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2011

DE Furst, EC Keystone, J Braun… - Annals of the …, 2012 - ard.bmj.com
As in previous years, the consensus group to consider the use of biological agents in the
treatment of rheumatic diseases met during the 13th Annual Workshop on Advances in …

Autoinflammatory diseases

I Touitou, I Koné-Paut - Best practice & research Clinical rheumatology, 2008 - Elsevier
Autoinflammatory diseases (AIDs) are illnesses caused by primary dysfunction of the innate
immune system. Proteins that are mutated in AIDs mediate the regulation of NFκB activation …

Роль интерлейкина 1 в развитии заболеваний человека

ЕЛ Насонов, МС Елисеев - Научно-практическая ревматология, 2016 - cyberleninka.ru
Иммуновоспалительные заболевания человека в зависимости от преобладающих
механизмов активации иммунитета разделяются на две основные категории …

Anakinra: new therapeutic approach in children with familial Mediterranean fever resistant to colchicine

R Roldan, AM Ruiz, MD Miranda, E Collantes - Joint Bone Spine, 2008 - Elsevier
Familial Mediterranean fever (FMF), a recessively inherited autoinflammatory disorder, is the
prototype of a group of disorders termed systemic autoinflammatory diseases. Such …

The use of interleukine-1 inhibitors in familial Mediterranean fever patients: a narrative review

V Hentgen, C Vinit, A Fayand… - Frontiers in …, 2020 - frontiersin.org
Purpose: Familial Mediterranean fever (FMF) is the most common monogenic auto-
inflammatory disease characterized by recurrent attacks of fever and serositis. It is …

[PDF][PDF] IL-1 inhibition in familial Mediterranean fever: clinical outcomes and expectations

F Kharouf, T Tsemach-Toren… - Clin Exp …, 2022 - clinexprheumatol.org
Familial Mediterranean fever (FMF) is a hereditary auto-inflammatory disease, characterised
by recurrent episodes of fever and serositis. Since 1972, colchicine has been the drug of …

Nanobodies dismantle post‐pyroptotic ASC specks and counteract inflammation in vivo

D Bertheloot, CWS Wanderley… - EMBO molecular …, 2022 - embopress.org
Inflammasomes sense intracellular clues of infection, damage, or metabolic imbalances.
Activated inflammasome sensors polymerize the adaptor ASC into micron‐sized “specks” to …