Anti-IL-1 treatment for secondary amyloidosis in an adolescent with FMF and Behçet's disease
Familial Mediterranean fever (FMF) is associated with mutations in the gene coding for pyrin
which lead to accentuated innate immune responses resulting in increased production of IL …
which lead to accentuated innate immune responses resulting in increased production of IL …
[HTML][HTML] Update on the management of colchicine resistant Familial Mediterranean Fever (FMF)
Abstract Background Familial Mediterranean Fever (FMF), an autoinflammatory disease, is
characterized by self-limited inflammatory attacks of fever and polyserositis along with high …
characterized by self-limited inflammatory attacks of fever and polyserositis along with high …
The clinical role of anakinra in the armamentarium against familial Mediterranean fever
ABSTRACT Introduction Familial Mediterranean Fever (FMF) is the most common
autoinflammatory disease that has mainly been treated with colchicine since 1972. A …
autoinflammatory disease that has mainly been treated with colchicine since 1972. A …
[PDF][PDF] Cutaneous amyloidoses and systemic amyloidoses with cutaneous involvement
S Schreml, RM Szeimies, T Vogt… - European Journal of …, 2010 - researchgate.net
Extracellular deposition of altered autologous protein (amyloid protein) within the dermis is
the hallmark of cutaneous amyloidoses and systemic amyloidoses with cutaneous …
the hallmark of cutaneous amyloidoses and systemic amyloidoses with cutaneous …
[PDF][PDF] Therapeutic approach to familial Mediterranean fever: a review update
Familial Mediterranean fever (FMF) is a hereditary disorder characterised by recurrent
attacks of fever with peritonitis or pleuritis, arthritis, myalgia or erysipelas-like skin lesions …
attacks of fever with peritonitis or pleuritis, arthritis, myalgia or erysipelas-like skin lesions …
Inflammasome and cytokine blocking strategies in autoinflammatory disorders
M Moll, JB Kuemmerle-Deschner - Clinical immunology, 2013 - Elsevier
Autoinflammatory disorders are characterized by usually unprovoked recurrent episodes of
features of inflammation caused by activation of the innate immune system. Many …
features of inflammation caused by activation of the innate immune system. Many …
Inflammasome-dependent cytokines at the crossroads of health and autoinflammatory disease
H Van Gorp, N Van Opdenbosch… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
As key regulators of both innate and adaptive immunity, it is unsurprising that the activity of
interleukin (IL)-1 cytokine family members is tightly controlled by decoy receptors …
interleukin (IL)-1 cytokine family members is tightly controlled by decoy receptors …
Anti-IL1 treatment in colchicine-resistant paediatric FMF patients: real life data from the HELIOS registry
Objectives FMF is a prototype of autoinflammatory diseases associated with excess IL1
production. Anti-IL1 treatments are the first-line alternatives in colchicine-resistant/intolerant …
production. Anti-IL1 treatments are the first-line alternatives in colchicine-resistant/intolerant …
Inflammasomes and rheumatic diseases: evolving concepts
PI Sidiropoulos, G Goulielmos… - Annals of the …, 2008 - ard.bmj.com
The realisation that the production of inflammatory cytokines in inflammatory rheumatic
diseases may be induced by non-infectious endogenous signals has encouraged …
diseases may be induced by non-infectious endogenous signals has encouraged …
[HTML][HTML] The central role of anti-IL-1 blockade in the treatment of monogenic and multi-factorial autoinflammatory diseases
S Federici, A Martini, M Gattorno - Frontiers in immunology, 2013 - frontiersin.org
Inherited autoinflammatory diseases are secondary to mutations of proteins playing a pivotal
role in the regulation of the innate immunity leading to seemingly unprovoked episodes of …
role in the regulation of the innate immunity leading to seemingly unprovoked episodes of …