The innate immune system serves to generate immediate host defenses against pathogens.
Advance in the mechanism of innate immunity has provided new insights into host-pathogen …

We report the case of a 35-years-old renal transplant patient known to have familial
Mediterranean fever with serum amyloid A (SAA)-amyloidosis, who presented with his …

While autoimmunity as cause of disease is well-established, other categories of immune-
mediated diseases that are not produced by targeting of self-antigens by antibodies is in the …

Aim Colchicine prophylaxis is the single most important factor in ameliorating familial
Mediterranean fever (FMF) for the prevention of both attacks and secondary amyloidosis …

The characterization of patients with recurrent inflammatory syndromes into distinct clinical
phenotypes provided early clues to the mode of inheritance of these conditions and …

Inflammation is a protective response to eliminate cytotoxic agents and pathogens. Various
factors are thought to be involved in the pathological changes in tissues caused by …

Furthermore, 10% of patients are unresponsive to colchicine (10). Recent short reports
demonstrate the efficacy of IL-1 receptor antagonist therapy (anakinra) in colchicine …

Inflammation, the classic quadrad of “rubor (redness), tumor (swelling), calor (heat), and
dolor (pain)”, is a fundamental concept of immunology and a common observation in clinical …

ABSTRACT Introduction: Familial Mediterranean fever (FMF) is the most common hereditary
autoinflammatory syndrome. The treatment of choice is colchicine. However,~ 40% of …

Objective. To develop and assess the validity and reliability of an adherence scale
concerning medical treatment in paediatric FMF patients. Methods. The Medication …