Epidemiological data highlight prostate cancer as a significant global health issue, with high
incidence and substantial impact on patients' quality of life. The prevalence of this disease is …

Prostate and lung cancers are among the most common cancer types, and they still need
more therapeutics. For this purpose, saquinavir (SAQ) was tested alone and in combination …

Precision oncology is an absolute need today due to the emergence of treatment resistance
and heterogeneity among cancerous profiles. Target-propelled cancer therapy is one of the …

The Golgi associated retrograde protein complex (GARP) is an evolutionarily conserved
component of Golgi membrane trafficking machinery that belongs to the Complexes …

Background: Germline mutations in BRCA2 have been linked to a higher risk of prostate
cancer (PCa), and high frequency of BRCA1 and BRCA2 (BRCA1/2) gene alterations was …

The gut microbiota helps to reveal the relationship between diseases, but the role of gut
microbiota in prostate cancer (PCa) is still unclear. Recent studies have found that the …

Background The goal of precision medicine in prostate cancer (PCa) is to individualize the
treatment according to the patient's germline mutation status. PCa has a very high rate of …

Background: Our study was designed to elucidate the morbidity trends of prostate cancer in
low-incidence countries. Methods: Data on prostate cancer were extracted from the 2019 …

Background Black men are more likely to be diagnosed with aggressive prostate cancer
(PC) and die from PC than white men. However, black men with metastatic castration …

Background Expression of CD44 receptor is associated with the onset of several tumors.
The intracellular domain of CD44 (CD44-ICD) has been implicated as a co-transcription …