Application of network pharmacology and molecular docking to elucidate the potential mechanism of Astragalus–Scorpion against prostate cancer

L Wu, Y Chen, M Chen, Y Yang, Z Che, Q Li, X You… - Andrologia, 2021 - Wiley Online Library
The present study aimed to investigate the molecular mechanism of the Astragalus–
Scorpion drug pair in the treatment of prostate cancer (PCa). We employed network …

Increased Risk of Hereditary Prostate Cancer in Italian Families with Hereditary Breast and Ovarian Cancer Syndrome Harboring Mutations in BRCA and in Other …

G D'Elia, G Caliendo, MM Tzioni, L Albanese… - Genes, 2022 - mdpi.com
Hereditary prostate cancer (HPCa) has the highest heritability of any cancer in men.
Interestingly, it occurs in several hereditary syndromes, including breast and ovarian cancer …

Prostate cancer age-standardised incidence increase between 2006 and 2016 in Gauteng Province, South Africa: A laboratory data-based analysis

N Cassim, A Ahmad, R Wadee, TR Rebbeck… - South African Medical …, 2021 - journals.co.za
Background. Prostate cancer (PCa) is the leading male neoplasm in South Africa (SA) and is
the second most frequently diagnosed cancer among men globally. Age-specific incidence …

Effect of selenium and lycopene on radiation sensitivity in prostate cancer patients relative to controls

VS Dhillon, P Deo, M Fenech - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer (PC) is the most common cancer in elderly men, but its
prevention by appropriate dietary interventions remains elusive. In this study, we show that …

Undergoing radical treatment for prostate cancer and its impact on wellbeing: A qualitative study exploring men's experiences

N Vyas, O Brunckhorst, L Fox, M Van Hemelrijck… - Plos one, 2022 - journals.plos.org
Introduction Quality of life in prostate cancer survivorship is becoming increasingly
important, with mental and social wellbeing recognised as key components. However …

Nanomedicine in cancer clinics: are we there yet?

PP Nayak, A Narayanan, AK Badekila… - Current Pathobiology …, 2021 - Springer
Abstract Purpose of Review Despite preclinical success of nanomedicine for anticancer
activity, the clinical success of the same has been very limited. This review evaluates and …

The Relationship between Telomere Length and Nucleoplasmic Bridges and Severity of Disease in Prostate Cancer Patients

VS Dhillon, P Deo, M Fenech - Cancers, 2023 - mdpi.com
Simple Summary Telomeres are essential to prevent telomere end fusions that cause the
formation of dicentric chromosomes and nucleoplasmic bridges (NPBs) which in turn induce …

δ-Catenin Participates in EGF/AKT/p21Waf Signaling and Induces Prostate Cancer Cell Proliferation and Invasion

Y Shen, HJ Lee, R Zhou, H Kim, G Chen… - International Journal of …, 2021 - mdpi.com
Prostate cancer (PCa) is the second most leading cause of death in males. Our previous
studies have demonstrated that δ-catenin plays an important role in prostate cancer …

Picropodophyllin inhibits the proliferation of human prostate cancer du145 and lncap cells via ros production and pi3k/akt pathway inhibition

X Zhu, X Chen, G Wang, D Lei, X Chen… - Biological and …, 2022 - jstage.jst.go.jp
The reactive oxygen species (ROS) and phosphatidylinositol 3-kinase (PI3K)/protein kinase
B (AKT) signaling pathway play critical roles in the pathogenesis of prostate cancer by …

Access to Prostate-Specific Antigen Testing and Mortality Among Men With Prostate Cancer

HS Iyer, BV Stone, C Roscoe, MC Hsieh… - JAMA Network …, 2024 - jamanetwork.com
Importance Prostate-specific antigen (PSA) screening for prostate cancer is controversial but
may be associated with benefit for certain high-risk groups. Objectives To evaluate …