Numerous studies have demonstrated that endothelial cells are capable of undergoing
endothelial to mesenchymal transition (EndMT), a newly recognized type of cellular …

Fibrosis denotes excessive scarring, which exceeds the normal wound healing response to
injury in many tissues. Although the extracellular matrix deposition appears unstructured …

Endothelial to mesenchymal transition (EndMT) is a process whereby an endothelial cell
undergoes a series of molecular events that lead to a change in phenotype toward a …

ABSTRACT Introduction: Systemic sclerosis (SSc) is a complex autoimmune connective
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …

Endothelial to mesenchymal transition (EndMT) is a complex biological process that gives
rise to cells with multipotent potential. EndMT is essential for the formation of the …

Circular RNAs (circRNAs) are highly expressed in the CNS and regulate physiological and
pathophysiological processes. However, the potential role of circRNAs in stroke remains …

Non-alcoholic fatty liver disease (NAFLD) and its complications are an expanding health
problem associated with the metabolic syndrome. Liver sinusoidal endothelial cells (LSECs) …

The inherent plasticity and resiliency of fibroblasts make this cell type a conventional tool for
basic research. But where do they come from, are all fibroblasts the same, and how do they …

Systemic sclerosis (SSc) is a complex disease characterized by early microvascular
abnormalities, immune dysregulation and chronic inflammation, and subsequent fibrosis of …

The clearance of damaged myelin sheaths is critical to ensure functional recovery from
neural injury. Here we show a previously unidentified role for microvessels and their lining …