Recent advances in mRNA cancer vaccines: meeting challenges and embracing opportunities
B Wang, J Pei, S Xu, J Liu, J Yu - Frontiers in immunology, 2023 - frontiersin.org
Since the successful application of messenger RNA (mRNA) vaccines in preventing COVID-
19, researchers have been striving to develop mRNA vaccines for clinical use, including …
19, researchers have been striving to develop mRNA vaccines for clinical use, including …
[HTML][HTML] Recent advances in the development of sialyltransferase inhibitors to control cancer metastasis: A comprehensive review
Metastasis accounts for the majority of cancer-associated mortalities, representing a huge
health and economic burden. One of the mechanisms that enables metastasis is …
health and economic burden. One of the mechanisms that enables metastasis is …
A journey of challenges and victories: a bibliometric worldview of nanomedicine since the 21st century
J Wang, W Zhao, Z Zhang, X Liu, T Xie… - Advanced …, 2024 - Wiley Online Library
Nanotechnology profoundly affects the advancement of medicine. Limitations in diagnosing
and treating cancer and chronic diseases promote the growth of nanomedicine. However …
and treating cancer and chronic diseases promote the growth of nanomedicine. However …
Biomaterials-mediated CRISPR/Cas9 delivery: recent challenges and opportunities in gene therapy
AK Dubey, E Mostafavi - Frontiers in Chemistry, 2023 - frontiersin.org
The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …
holds tremendous potential. This innovative approach combines the advantages of …
An overview of the use of nanoparticles in vaccine development
Vaccines represent one of the most significant advancements in public health since they
prevented morbidity and mortality in millions of people every year. Conventionally, vaccine …
prevented morbidity and mortality in millions of people every year. Conventionally, vaccine …
Metal–Drug Coordination Nanoparticles and Hydrogels for Enhanced Delivery
KY Wong, Z Nie, MS Wong, Y Wang… - Advanced Materials, 2024 - Wiley Online Library
Drug delivery is a key component of nanomedicine, and conventional delivery relies on the
adsorption or encapsulation of drug molecules to a nanomaterial. Many delivery vehicles …
adsorption or encapsulation of drug molecules to a nanomaterial. Many delivery vehicles …
Delivery of immunostimulatory cargos in nanocarriers enhances anti-tumoral nanovaccine efficacy
J Schunke, V Mailänder, K Landfester… - International Journal of …, 2023 - mdpi.com
Finding a long-term cure for tumor patients still represents a major challenge.
Immunotherapies offer promising therapy options, since they are designed to specifically …
Immunotherapies offer promising therapy options, since they are designed to specifically …
Lipid Nanoparticle (LNP) Delivery Carrier-Assisted Targeted Controlled Release mRNA Vaccines in Tumor Immunity
L Wu, X Li, X Qian, S Wang, J Liu, J Yan - Vaccines, 2024 - mdpi.com
In recent years, lipid nanoparticles (LNPs) have attracted extensive attention in tumor
immunotherapy. Targeting immune cells in cancer therapy has become a strategy of great …
immunotherapy. Targeting immune cells in cancer therapy has become a strategy of great …
Advancing CAR-based immunotherapies in solid tumors: CAR-macrophages and neutrophils
Y Liang, Q Xu, Q Gao - Frontiers in Immunology, 2023 - frontiersin.org
Macrophages and neutrophils are the main components of the innate immune system and
play important roles in promoting angiogenesis, extracellular matrix remodeling, cancer cell …
play important roles in promoting angiogenesis, extracellular matrix remodeling, cancer cell …
Role of NLRP3 inflammasome in nanoparticle adjuvant-mediated immune response
M Ahmed, P Kurungottu, K Swetha, S Atla… - Biomaterials …, 2024 - pubs.rsc.org
The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin
domain-containing 3 (NLRP3) inflammasome is pivotal in orchestrating the immune …
domain-containing 3 (NLRP3) inflammasome is pivotal in orchestrating the immune …