Atherosclerosis is an inflammatory disease of the large arteries that is the major cause of
cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the …

Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation.
Inflammation is one common and effective physiological event that protects against various …

Mortality among patients with chronic kidney disease (CKD) is largely a consequence of
cardiovascular disease (CVD) and is a particular concern given the increasing prevalence of …

Hypertension is regarded as the most prominent risk factor for cardiovascular diseases,
which have become a primary cause of death, and recent research has demonstrated that …

Neurotransmitters have been well documented to determine immune cell fates; however,
whether and how γ-amino butyric acid (GABA) shapes the function of innate immune cells is …

The CANTOS (Canakinumab Anti-inflammatory Thrombosis Outcome Study) and colchicine
trials suggest an important role of inflammasomes and their major product IL-1β (interleukin …

The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates
innate immune responses by activating caspase-1 and the inflammatory cytokines …

The culprits of atherosclerosis are endothelial damage, local disorders of lipid metabolism,
and progressive inflammation. Early atherosclerosis is typically difficult to diagnose in time …

The public health issue of glucolipid metabolic disorders (GLMD) has grown significantly,
posing a grave threat to human wellness. Its prevalence is rising yearly and tends to affect …

M2 macrophage-mediated tissue repair plays an important role in acute myocardial
infarction (AMI). Additionally, VSIG4, which is mainly expressed on tissue-resident and M2 …