[HTML][HTML] Immune pathway upregulation and lower genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS

CMM Wai, S Chen, T Phyu, S Fan, SM Leong… - …, 2022 - ncbi.nlm.nih.gov
Abstract Primary Epstein-Barr virus (EBV)-positive nodal T/NK-cell lymphoma (PTCL-EBV) is
a poorly understood disease which shows features resembling extranodal NK/T-cell …

Insight into oncogenic viral pathways as drivers of viral cancers: implication for effective therapy

AME Elkhalifa, SU Nabi, OS Shah, SM Bashir… - Current …, 2023 - mdpi.com
As per a recent study conducted by the WHO, 15.4% of all cancers are caused by infectious
agents of various categories, and more than 10% of them are attributed to viruses. The …

The roles of miRNAs and lncRNAs in Epstein-Barr virus associated epithelial cell tumors

H Wang, W Liu, B Luo - Virus Research, 2021 - Elsevier
Epstein-Barr virus (EBV) infection is highly prevalent in the population and is known to be
associated with a variety of human tumors, such as nasopharyngeal carcinoma, gastric …

Molecular characterisation of Epstein–Barr virus in classical Hodgkin lymphoma

V Begić, P Korać, S Gašparov, M Rozman… - International journal of …, 2022 - mdpi.com
Hodgkin lymphomas (HLs) are a heterogeneous group of lymphoid neoplasia associated
with Epstein–Barr virus (EBV) infection. EBV, considered to be an important etiological co …

Characterizing expression and regulation of gamma-herpesviral circular RNAs

T Tagawa, D Oh, J Santos, S Dremel… - Frontiers in …, 2021 - frontiersin.org
Multiple herpesviruses have been recently found to encode viral circular RNAs. Like cellular
circular RNAs, these RNAs lack poly-A tails and their 5′ and 3′ ends have been joined …

[HTML][HTML] Epstein-Barr Virus BGLF2 commandeers RISC to interfere with cellular miRNA function

AM Campbell, F Carlos, E Marcon, J Greenblatt… - PLoS …, 2022 - journals.plos.org
The Epstein-Barr virus (EBV) BGLF2 protein is a tegument protein with multiple effects on
the cellular environment, including induction of SUMOylation of cellular proteins. Using …

[HTML][HTML] Analyzing the Impact of the Highest Expressed Epstein–Barr Virus-Encoded microRNAs on the Host Cell Transcriptome

T Hohmann, U Hohmann, F Dehghani… - … Journal of Molecular …, 2024 - ncbi.nlm.nih.gov
Abstract The Epstein–Barr virus (EBV) has a very high prevalence (> 90% in adults),
establishes a lifelong latency after primary infection, and exerts an oncogenic potential. This …

Circulating microRNAs as the potential diagnostic and prognostic biomarkers for nasopharyngeal carcinoma

TAH Le, TD Lao - Genes, 2022 - mdpi.com
microRNAs are endogenous non-coding miRNAs, 19–25 nucleotides in length, that can be
detected in the extracellular environment in stable forms, named circulating miRNAs (CIR …

Carcinogenic mechanisms of virus-associated lymphoma

Y Zhang, W Guo, Z Zhan, O Bai - Frontiers in Immunology, 2024 - frontiersin.org
The development of lymphoma is a complex multistep process that integrates numerous
experimental findings and clinical data that have not yet yielded a definitive explanation …

The viral etiology of EBV-associated gastric cancers contributes to their unique pathology, clinical outcomes, treatment responses and immune landscape

MY Salnikov, KM MacNeil, JS Mymryk - Frontiers in Immunology, 2024 - frontiersin.org
Epstein-Barr virus (EBV) is a pathogen known to cause a number of malignancies, often
taking years for them to develop after primary infection. EBV-associated gastric cancer …