[HTML][HTML] Gut microbial metabolites in depression: understanding the biochemical mechanisms

G Caspani, S Kennedy, JA Foster, J Swann - Microbial Cell, 2019 - ncbi.nlm.nih.gov
Gastrointestinal and central function are intrinsically connected by the gut microbiota, an
ecosystem that has co-evolved with the host to expand its biotransformational capabilities …

The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta‐review of meta‐analyses of randomized controlled trials

J Firth, SB Teasdale, K Allott, D Siskind… - World …, 2019 - Wiley Online Library
The role of nutrition in mental health is becoming increasingly acknowledged. Along with
dietary intake, nutrition can also be obtained from “nutrient supplements”, such as …

Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry …

J Sarris, A Ravindran, LN Yatham, W Marx… - The World Journal of …, 2022 - Taylor & Francis
Objectives The therapeutic use of nutrient-based 'nutraceuticals' and plant-based
'phytoceuticals' for the treatment of mental disorders is common; however, despite recent …

Treatment-resistant depression revisited: a glimmer of hope

A Halaris, E Sohl, EA Whitham - Journal of personalized medicine, 2021 - mdpi.com
Major Depressive Disorder (MDD) is a highly prevalent psychiatric disorder worldwide. It
causes individual suffering, loss of productivity, increased health care costs and high suicide …

Annual Research Review: Defining and treating pediatric treatment‐resistant depression

JB Dwyer, A Stringaris, DA Brent… - Journal of Child …, 2020 - Wiley Online Library
Background Adolescent major depressive disorder (MDD) is a significant health problem,
associated with substantial morbidity, cost, and mortality. Depression is a significant risk …

Depression-associated gut microbes, metabolites and clinical trials

M Wang, Z Song, S Lai, F Tang, L Dou… - Frontiers in …, 2024 - frontiersin.org
Depression is one of the most prevalent mental disorders today. Over the past decade, there
has been considerable attention given to the field of gut microbiota associated with …

Natural health products, dietary minerals and over-the-counter medications as add-on therapies to antidepressants in the treatment of major depressive disorder: a …

P Dome, L Tombor, J Lazary, X Gonda, Z Rihmer - Brain Research Bulletin, 2019 - Elsevier
Given the moderate efficacy of the currently available antidepressants (ADs) in the treatment
of major depressive disorder (MDD), the identification of agents that are both able to …

Association between folate and health outcomes: an umbrella review of meta-analyses

Y Bo, Y Zhu, Y Tao, X Li, D Zhai, Y Bu, Z Wan… - Frontiers in Public …, 2020 - frontiersin.org
Background: There is no study that has systematically investigated the breadth and validity
of the associations of folate and multiple health outcomes. We aimed to evaluate the …

New agents and perspectives in the pharmacological treatment of major depressive disorder

M Sanches, J Quevedo, JC Soares - Progress in Neuro …, 2021 - Elsevier
Despite the important advances in the understanding of the pathophysiology of MDD, a
large proportion of depressed patients do not respond well to currently available …

The effects of folic acid supplementation on depression in adults: A systematic review and meta-analysis of randomized controlled trials

P Khalili, O Asbaghi, L Aghakhani, CCT Clark… - Nutrition & Food …, 2023 - emerald.com
Purpose This study aims, a systematic review and meta-analysis, to evaluate the effects of
folic acid (folate) on patients with depression. Design/methodology/approach Related …