Protein kinases: The key contributors in pathogenesis and treatment of nonalcoholic fatty liver disease-derived hepatocellular carcinoma

R Liu, MP Qian, YY Cui - Metabolism, 2023 - Elsevier
Protein kinases (PKs), one of the largest protein families, can be further divided into different
groups based on their substrate or structure and function. PKs are important signaling …

Role of the type 3 cytokines IL-17 and IL-22 in modulating metabolic dysfunction-associated steatotic liver disease

MN Abdelnabi, GS Hassan, NH Shoukry - Frontiers in Immunology, 2024 - frontiersin.org
Metabolic dysfunction-associated steatotic liver disease (MASLD) comprises a spectrum of
liver diseases that span simple steatosis, metabolic dysfunction-associated steatohepatitis …

Effects of sodium-glucose co-transporter 2 inhibitors on liver fibrosis in non-alcoholic fatty liver disease patients with type 2 diabetes mellitus: An updated meta …

Z Jin, Y Yuan, C Zheng, S Liu, H Weng - Journal of Diabetes and its …, 2023 - Elsevier
Background and aim Sodium-glucose co-transporter 2 inhibitors (SGLT2i) has been verified
to improve Non-alcoholic fatty liver disease (NAFLD) in previous clinical practice. We mainly …

A global survey of health care workers' awareness of non‐alcoholic fatty liver disease: The AwareNASH survey

S Driessen, VD de Jong, KC van Son… - United European …, 2023 - Wiley Online Library
Background The estimated global prevalence and burden of non‐alcoholic fatty liver
disease (NAFLD) and its advanced stage, non‐alcoholic steatohepatitis (NASH), is …

Potential Therapeutic Strategies in the Treatment of Metabolic-Associated Fatty Liver Disease

A Bołdys, Ł Bułdak, M Maligłówka, S Surma, B Okopień - Medicina, 2023 - mdpi.com
Metabolic-associated Fatty Liver Disease is one of the outstanding challenges in
gastroenterology. The increasing incidence of the disease is undoubtedly connected with …

Recent updates on pharmacologic therapy in non-alcoholic fatty liver disease

Y Chang, SW Jeong, JY Jang - Clinical and Molecular Hepatology, 2023 - e-cmh.org
Since there are currently no US Food and Drug Administration (FDA)-approved drugs for the
treatment of non-alcoholic steatohepatitis (NASH), various NASH treatments are under …

Albumin-fused thioredoxin ameliorates high-fat diet-induced non-alcoholic steatohepatitis

R Murata, H Watanabe, R Iwakiri, M Chikamatsu… - Heliyon, 2024 - cell.com
The pathogenesis of non-alcoholic steatohepatitis (NASH) involves the simultaneous
interaction of multiple factors such as lipid accumulation, oxidative stress, and inflammatory …

Extracellular Superoxide Dismutase Attenuates Hepatic Oxidative Stress in Nonalcoholic Fatty Liver Disease through the Adenosine Monophosphate-Activated …

H Nam, JH Lim, TW Kim, EN Kim, SJ Oum, SH Bae… - Antioxidants, 2023 - mdpi.com
Oxidative stress is key in type 2 diabetes-associated nonalcoholic fatty liver disease
(NAFLD). We explored whether extracellular superoxide dismutase (EC-SOD) activates …

Thiazolidinedione use is associated with a borderline lower risk of multiple myeloma and a significantly lower risk of death in patients with type 2 diabetes mellitus in …

CH Tseng - Cancers, 2023 - mdpi.com
Simple Summary The effects of thiazolidinedione (TZD) on multiple myeloma have not been
investigated in humans. The reimbursement database of Taiwan's National Health …

[HTML][HTML] Lean vs. obese phenotypes of nonalcoholic fatty liver disease: similar or different?

HS Chun, M Lee - Clinical and molecular hepatology, 2023 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide, and its incidence and related complications are expected to rise with the global …