For over half a century, male rodents have been the default model organism in preclinical
neuroscience research, a convention that has likely contributed to higher rates of …

Although most patients with chronic pain are women, the preclinical literature regarding pain
processing and the pathophysiology of chronic pain has historically been derived …

Fibromyalgia (FM) is a common chronic pain disorder that presents diagnostic challenges
for clinicians. Several classification, diagnostic and screening criteria have been developed …

Background Reports of the overall chronic pain prevalence and its associated demographic
characteristics among adolescents vary greatly across existing studies. Using internationally …

The current study included randomized controlled trials (RCTs) to assess the benefits of
Acceptance and commitment therapy (ACT) for chronic pain. Searches were conducted in …

Chronic pain is nowadays used as an umbrella term referring to a wide range of clinical
conditions, such as fibromyalgia, migraine, or long-standing pain states without actual …

Abstract Mu-Opioid Receptors (MORs) are well-known for participating in analgesia,
sedation, drug addiction, and other physiological functions. Although MORs have been …

Previous systematic reviews have summarized the prevalence and impact of chronic pain in
“average” pediatric (ie, school-age children) and adult (ie, middle-aged individuals) age …

Recent research has highlighted a need for the psychometric evaluation of instruments
targeting core domains of the pain experience in chronic pain populations. In this study, the …

Understanding why people vary in their experience and response to pain is central to the
development of better, more targeted, personalised, treatments for pain. Sex and gender …