Cell-permeable succinate rescues mitochondrial respiration in cellular models of amiodarone toxicity
AM Bețiu, I Chamkha, E Gustafsson, E Meijer… - International Journal of …, 2021 - mdpi.com
Amiodarone is a potent antiarrhythmic drug and displays substantial liver toxicity in humans.
It has previously been demonstrated that amiodarone and its metabolite …
It has previously been demonstrated that amiodarone and its metabolite …
[HTML][HTML] Amiodarone but not propafenone impairs bioenergetics and autophagy of human myocardial cells
A Krajčová, V Němcová, M Halačová, P Waldauf… - Toxicology and Applied …, 2023 - Elsevier
Cardiac and extra-cardiac side effects of common antiarrhythmic agents might be related to
drug-induced mitochondrial dysfunction. Supratherapeutic doses of amiodarone have been …
drug-induced mitochondrial dysfunction. Supratherapeutic doses of amiodarone have been …
Characterization of the Omija (Schisandra chinensis) Extract and Its Effects on the Bovine Sperm Vitality and Oxidative Profile during In Vitro Storage
Schisandra chinensis is a woody vine native to China, Korea, and Russia, which has been
used as a traditional herbal remedy to treat male infertility. As very little information is …
used as a traditional herbal remedy to treat male infertility. As very little information is …
High-voltage electric discharge extraction of bioactive compounds from the cocoa bean shell
High-Voltage Electric Discharge Extraction of Bioactive Compounds from the Cocoa Bean Shell+
Page 1 S. Jokić et al., High-Voltage Electric Discharge Extraction of Bioactive Compounds …
Page 1 S. Jokić et al., High-Voltage Electric Discharge Extraction of Bioactive Compounds …
Grape seed proanthocyanidins improves mitochondrial function and reduces oxidative stress through an increase in sirtuin 3 expression in EA. hy926 cells in high …
AF Cerbaro, VSB Rodrigues, M Rigotti… - Molecular Biology …, 2020 - Springer
Proanthocyanidins are phenolic compounds abundant in the diet, commonly found in
grapes and derivatives, foods known for their health-promoting benefits. There is previous …
grapes and derivatives, foods known for their health-promoting benefits. There is previous …
The inhibitory mechanisms of losartan and vitamin D on amiodarone‐induced lung inflammation in rats: Role of mitogen‐activated protein kinases/activator protein‐1
S Al‐Hassan, H Attia, H Alomar… - Journal of Biochemical …, 2021 - Wiley Online Library
Amiodarone (AMD), an antiarrhythmic drug, is used cautiously due to its lung toxicity that is
characterized by alveolar inflammation followed by fatal fibrosis. AMD induces lung …
characterized by alveolar inflammation followed by fatal fibrosis. AMD induces lung …
Dietary cocoa flavanols enhance mitochondrial function in skeletal muscle and modify whole-body metabolism in healthy mice
FN Daussin, A Cuillerier, J Touron, S Bensaid, B Melo… - Nutrients, 2021 - mdpi.com
Mitochondrial dysfunction is widely reported in various diseases and contributes to their
pathogenesis. We assessed the effect of cocoa flavanols supplementation on mitochondrial …
pathogenesis. We assessed the effect of cocoa flavanols supplementation on mitochondrial …
[HTML][HTML] Ethyl-acetate fraction of Trichilia catigua protects against oxidative stress and neuroinflammation after cerebral ischemia/reperfusion
J Godinho, AB de Sa-Nakanishi, LS Moreira… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Trichilia catigua A. Juss (Meliaceae) preparations have
been used in folk medicine to alleviate fatigue, stress, and improve memory. Antinociceptive …
been used in folk medicine to alleviate fatigue, stress, and improve memory. Antinociceptive …
Potential protective effect of catechin on doxorubicin-induced cardiotoxicity in adult male albino rats
AS Saleh Ahmed - Toxicology Mechanisms and Methods, 2022 - Taylor & Francis
Doxorubicin (DOX) is the most effective and frequently used anticancer drug but its
cardiotoxicity is the most important side effect that limits the clinical use of it. This study was …
cardiotoxicity is the most important side effect that limits the clinical use of it. This study was …
Cocoa flavanols, Nrf2 activation, and oxidative stress in peripheral artery disease: mechanistic findings in muscle based on outcomes from a randomized trial
A Ismaeel, MM McDermott, JK Joshi… - … of Physiology-Cell …, 2024 - journals.physiology.org
The pathophysiology of muscle damage in peripheral artery disease (PAD) includes
increased oxidant production and impaired antioxidant defenses. Epicatechin (EPI), a …
increased oxidant production and impaired antioxidant defenses. Epicatechin (EPI), a …