Nanotechnology-based ocular drug delivery systems: recent advances and future prospects
S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …
Considerations for polymers used in ocular drug delivery
MM Allyn, RH Luo, EB Hellwarth… - Frontiers in …, 2022 - frontiersin.org
Purpose Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …
been seen in the most common causes including glaucoma, age-related macular …
Ocular drug delivery to the retina: current innovations and future perspectives
HM Kim, SJ Woo - Pharmaceutics, 2021 - mdpi.com
Treatment options for retinal diseases, such as neovascular age-related macular
degeneration, diabetic retinopathy, and retinal vascular disorders, have markedly expanded …
degeneration, diabetic retinopathy, and retinal vascular disorders, have markedly expanded …
Dexamethasone: insights into pharmacological aspects, therapeutic mechanisms, and delivery systems
VS Madamsetty, R Mohammadinejad… - ACS biomaterials …, 2022 - ACS Publications
Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …
Polymeric long-acting drug delivery systems (LADDS) for treatment of chronic diseases: Inserts, patches, wafers, and implants
Non-oral long-acting drug delivery systems (LADDS) encompass a range of technologies for
precisely delivering drug molecules into target tissues either through the systemic circulation …
precisely delivering drug molecules into target tissues either through the systemic circulation …
Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy
J Wei, J Mu, Y Tang, D Qin, J Duan, A Wu - Journal of nanobiotechnology, 2023 - Springer
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and
related conditions, pose considerable challenges to effective management and treatment …
related conditions, pose considerable challenges to effective management and treatment …
Treatment of non-infectious corneal injury: review of diagnostic agents, therapeutic medications, and future targets
DH Dang, KM Riaz, D Karamichos - Drugs, 2022 - Springer
Corneal injuries can occur secondary to traumatic, chemical, inflammatory, metabolic,
autoimmune, and iatrogenic causes. Ocular infection may frequently occur concurrent to …
autoimmune, and iatrogenic causes. Ocular infection may frequently occur concurrent to …
[HTML][HTML] MiRNA 24-3p-rich exosomes functionalized DEGMA-modified hyaluronic acid hydrogels for corneal epithelial healing
X Sun, W Song, L Teng, Y Huang, J Liu, Y Peng, X Lu… - Bioactive Materials, 2023 - Elsevier
The damage of corneal epithelium may lead to the formation of irreversible corneal opacities
and even blindness. The migration rate of corneal epithelial cells directly affects corneal …
and even blindness. The migration rate of corneal epithelial cells directly affects corneal …
[HTML][HTML] Thermo-responsive Diels-Alder stabilized hydrogels for ocular drug delivery of a corticosteroid and an anti-VEGF fab fragment
BC Ilochonwu, SA Van Der Lugt, A Annala… - Journal of Controlled …, 2023 - Elsevier
In the present study, a novel in situ forming thermosensitive hydrogel system was
investigated as a versatile drug delivery system for ocular therapy. For this purpose, two …
investigated as a versatile drug delivery system for ocular therapy. For this purpose, two …
Reverse engineering the Ozurdex dexamethasone intravitreal implant
Ozurdex is a biodegradable implant formulated for sustained-release delivery of the
corticosteroid dexamethasone to the posterior segment of the eye. The small, rod-shaped …
corticosteroid dexamethasone to the posterior segment of the eye. The small, rod-shaped …