Embryonic development in teleosts is profoundly affected by environmental conditions,
particularly temperature and dissolved oxygen concentrations. The environment determines …

Remodeling is a stringently controlled process that enables adequate response of muscle
cells to constant physical stresses. In this process, different kinds of stimuli have to be …

Myostatin is a transforming growth factor β superfamily member and is known as an inhibitor
of skeletal muscle cell proliferation and differentiation. Exposure to myostatin induces G 1 …

The cytokines of transforming growth factor β (TGF-β) and its superfamily members are
potent regulators of tumorigenesis and multiple cellular events. Myostatin is a member of …

Wooden breast is a muscle disorder affecting modern commercial broiler chickens that
causes a palpably firm pectoralis major muscle and severe reduction in meat quality. Most …

Myostatin (Mstn) is a secreted growth factor predominately expressed in skeletal muscle that
negatively regulates skeletal muscle mass. Recent studies have indicated that loss function …

Muscle growth and development are important aspects of chicken meat production, but the
underlying regulatory mechanisms remain unclear and need further exploration. CRISPR …

In an attempt to identify potential therapeutic targets for the correction of muscle wasting, the
gene expression of several pivotal proteins involved in protein metabolism was investigated …

Background Myostatin (MSTN), a member of the TGF-β superfamily, has been identified as a
negative regulator of skeletal muscle mass. Inactivating mutations in the MSTN gene are …

Myostatin (Mstn) is postulated to be a key determinant of muscle loss and cachexia in
cancer. However, no experimental evidence supports a role for Mstn in cancer, particularly …