A holistic review on Cryptococcus neoformans

SS Rathore, J Sathiyamoorthy, C Lalitha… - Microbial …, 2022 - Elsevier
Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

The regulation of filamentous growth in yeast

PJ Cullen, GF Sprague Jr - Genetics, 2012 - academic.oup.com
Filamentous growth is a nutrient-regulated growth response that occurs in many fungal
species. In pathogens, filamentous growth is critical for host–cell attachment, invasion into …

The evolution of sex: a perspective from the fungal kingdom

SC Lee, M Ni, W Li, C Shertz… - … and molecular biology …, 2010 - Am Soc Microbiol
Sex is shrouded in mystery. Not only does it preferentially occur in the dark for both fungi
and many animals, but evolutionary biologists continue to debate its benefits given costs in …

Coevolution of morphology and virulence in Candida species

DS Thompson, PL Carlisle, D Kadosh - Eukaryotic cell, 2011 - Am Soc Microbiol
Many of the major human fungal pathogens are known to undergo morphological changes,
which in certain cases are associated with virulence. Although there has been an intense …

The dynamic fungal genome: polyploidy, aneuploidy and copy number variation in response to stress

P Vande Zande, X Zhou… - Annual review of …, 2023 - annualreviews.org
Fungal species have dynamic genomes and often exhibit genomic plasticity in response to
stress. This genome plasticity often comes with phenotypic consequences that affect fitness …

Calcineurin Plays Key Roles in the Dimorphic Transition and Virulence of the Human Pathogenic Zygomycete Mucor circinelloides

SC Lee, A Li, S Calo, J Heitman - PLoS pathogens, 2013 - journals.plos.org
Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This
switch alters host-microbe interactions and is critical for pathogenicity. However, in …

Evolution of eukaryotic microbial pathogens via covert sexual reproduction

J Heitman - Cell host & microbe, 2010 - cell.com
Sexual reproduction enables eukaryotic organisms to reassort genetic diversity and purge
deleterious mutations, producing better-fit progeny. Sex arose early and pervades …

The Link between Morphotype Transition and Virulence in Cryptococcus neoformans

L Wang, B Zhai, X Lin - PLoS pathogens, 2012 - journals.plos.org
Cryptococcus neoformans is a ubiquitous human fungal pathogen. This pathogen can
undergo morphotype transition between the yeast and the filamentous form and such …

Epidemiology of invasive fungal infections in Latin America

J Sifuentes-Osornio, DE Corzo-León… - Current fungal infection …, 2012 - Springer
The pathogenic role of invasive fungal infections (IFIs) has increased during the past two
decades in Latin America and worldwide, and the number of patients at risk has risen …