Computer-aided drug designing (CADD) relates to drug discovery, also characterized as a
cost-effective and active tool that manages or creates theoretical models that would be used …

We present here an extended protein–RNA docking benchmark composed of 71 test cases
in which the coordinates of the interacting protein and RNA molecules are available from …

Recently, the ability to interact with messenger RNA (mRNA) has been reported for a
number of known RNA-binding proteins, but surprisingly also for different proteins without …

Covalent modifications of standard DNA/RNA nucleobases affect epigenetic regulation of
gene expression by modulating interactions between nucleic acids and protein readers. We …

Despite the great importance of nucleic acid–protein interactions in the cell, our
understanding of their physico-chemical basis remains incomplete. In order to address this …

Weak protein–protein interactions may be important to binding cooperativity. A panel of
seven fluorescently labeled tracer monoclonal IgG antibodies, differing in variable (V) and …

Targeting the protein− RNA interaction of LIN28 and let‐7 is a promising strategy for the
development of novel anticancer therapeutics. However, a limited number of small‐molecule …

RNA-binding proteins (RBPs) play key roles in RNA metabolism and post-transcriptional
regulation. Computational methods have been developed separately for prediction of RBPs …

Background The understanding of the importance of RNA has dramatically changed over
recent years. As in the case of proteins, the function of an RNA molecule is encoded in its …

Understanding the process of protein–RNA interaction is essential for structural biology. The
thermodynamic process is an important part to uncover the protein–RNA interaction …