RNA-binding proteins are functionally diverse within cells, being involved in RNA-
metabolism, translation, DNA damage repair, and gene regulation at both the transcriptional …

Protein-RNA complexes formed by specific recognition between RNA and RNA-binding
proteins play an important role in biological processes. More than a thousand of such …

Molecular modeling by means of docking and molecular dynamics (MD) has become an
integral part of early drug discovery projects, enabling the screening and enrichment of large …

Proteins are the bricks and mortar of cells, playing structural and functional roles. In order to
perform their function, they interact with each other as well as with other biomolecules such …

Motivation The main function of protein–RNA interaction is to regulate the expression of
genes. Therefore, studying protein–RNA interactions is of great significance. The information …

Networks of protein–RNA interactions is likely to be larger than protein–protein and protein–
DNA interaction networks because RNA transcripts are encoded tens of times more than …

Non-coding RNAs (ncRNAs), generated from nonprotein coding DNA sequences, constitute
98–99% of the human genome. Non-coding RNAs encompass diverse functional classes …

Protein-RNA complexes provide a wide range of essential functions in the cell. Their atomic
experimental structure solving, despite essential to the understanding of these functions, is …

The thermodynamics of protein–nucleic acid interactions (PNIs) is crucial for elucidating the
mechanisms of molecular recognition and pathological consequences. The Protein–Nucleic …