Virtual interactomics of proteins from biochemical standpoint

J Kubrycht, K Sigler, P Souček - Molecular biology international, 2012 - Wiley Online Library
Virtual interactomics represents a rapidly developing scientific area on the boundary line of
bioinformatics and interactomics. Protein‐related virtual interactomics then comprises …

蛋白质-RNA 相互作用界面预测与设计

黄阳玉, 阳秀凤, 李昊田, 纪晓峰, 程洪礼, 赵蕴杰… - 物理化学 …, 2012 - whxb.pku.edu.cn
蛋白质-RNA 之间的相互作用是蛋白质在细胞里面行使功能的重要方式之一.
结构生物学家利用实验手段可以得到蛋白质-RNA 复合物的三维结构, 通过原子水平的晶体结构 …

[HTML][HTML] Statistical potentials for RNA-protein interactions optimized by CMA-ES

T Kimura, N Yasuo, M Sekijima, B Lustig - Journal of Molecular Graphics …, 2022 - Elsevier
Characterizing RNA-protein interactions remains an important endeavor, complicated by the
difficulty in obtaining the relevant structures. Evaluating model structures via statistical …

Development of RNA stiffness parameters and analysis on protein-RNA binding specificity: comparison with DNA

M Michael Gromiha - Current Bioinformatics, 2012 - ingentaconnect.com
It has been well established that the elastic character of DNA plays an important role in
protein-DNA binding specificity. In this work, we have analyzed the role of elasticity to …

[PDF][PDF] Exploring the RNA Recognition Motif: A computational analysis of RRM-RNA recognition and the interplay between multiple RRM domains

JR Martínez, WF Vranken - 2023 - researchportal.vub.be
The RNA recognition motif (RRM) is the most prevalent RNA-binding protein domain in
eukaryotes and is involved in most of RNA metabolism processes. Their RNA binding …

[PDF][PDF] Fragment-based modelling of protein-RNA complexes for protein design

A Kravchenko - 2023 - theses.hal.science
3.2. 1 Coarse-Grained Representation ssRNA'TTRACT uses a coarse-grained
representation and a knowledge-based scoring function [168, 257, 256]. Each amino acid is …

Molecular-Docking-Based Anti-Allergic Drug Design

A Basu, P Basak, A Sarkar - Applied Case Studies and Solutions in …, 2016 - igi-global.com
Allergens are foreign proteins that when come in contact of part (s) of human body stimulate
the production of immunoglobulin types of proteins (antibodies). These allergens react with …

Bioinformatic Methods to Discover Cis-regulatory Elements in mRNAs

SG Stevens, CM Brown - Springer Handbook of Bio-/Neuroinformatics, 2014 - Springer
Cis-regulatory elements play a number of important roles in determining the fate of
messenger RNAs (mRNAs). Due to these elements, mRNAs may be translated with …

[PDF][PDF] Homology modeling of the complex between the Repressor of Primer protein and its cognate RNA kissing complex

D Nikolopoulou - 2022 - utopia.duth.gr
The ROP protein is a dimeric protein with an α-helix bundle conformation that is found in
bacteria. ROP protein is involved in the replication regulation mechanism of the …

[HTML][HTML] Scoring functions for protein-RNA complex structure prediction: advances, applications, and future directions

L Qiu, X Zou - Communications in information and systems, 2020 - ncbi.nlm.nih.gov
Protein-RNA interaction is among the most essential of biological events in living cells,
being involved in protein synthesizing, RNA processing and transport, DNA transcription …