Ferroptosis is a programmed iron-dependent cell death characterized by accumulation of
lipid peroxides (LOOH) and redox disequilibrium. Ferroptosis shows unique characteristics …

The promise of human induced pluripotent stem cells (iPSCs) lies in their ability to serve as
a starting material for autologous, or patient‐specific, stem cell–based therapies. Since the …

We report the implantation of patient-derived midbrain dopaminergic progenitor cells,
differentiated in vitro from autologous induced pluripotent stem cells (iPSCs), in a patient …

The specific loss of midbrain dopamine neurons (mDANs) causes major motor dysfunction
in Parkinson's disease, which makes cell replacement a promising therapeutic approach …

In pursuit of treating Parkinson's disease with cell replacement therapy, differentiated
induced pluripotent stem cells (iPSC) are an ideal source of midbrain dopaminergic (mDA) …

In Parkinson's disease (PD), there are currently no effective therapies to prevent or slow
down disease progression. Cell replacement therapy using human pluripotent stem cell …

Cell therapies as potential treatments for Parkinson's disease first gained traction in the
1980s, owing to the clinical success of trials that used transplants of foetal midbrain …

Rationale: Parkinson's disease (PD) is a prevalent neurodegenerative disorder that is
characterized by degeneration of dopaminergic neurons (DA) at the substantia nigra pas …

Abstract Parkinson's disease (PD), characterized by loss of nigrostriatal dopaminergic
neurons, is one of the most predominant neurodegenerative diseases affecting the elderly …

The degeneration of nigral (A9) dopaminergic (DA) neurons causes motor symptoms in
Parkinson's disease (PD). We use small-molecule compounds to direct the differentiation of …