Colon targeted drug delivery systems have gained a great deal of attention as potential
carriers for the local treatment of colonic diseases with reduced systemic side effects and …

Various diseases remain untreated due to lack of suitable therapeutic moiety or a suitable
drug delivery device, especially where toxicities and side effects are the primary reason for …

Conventional cancer treatment modalities have several limitations including lack of sufficient
efficacy, serious untoward toxicity, as well as innate and acquired drug resistance. In …

Background In cancer therapy, molecularly targeted agents have the potential to maximize
antitumor efficacy while minimizing treatment-related toxicity. However, these agents may …

As per the WHO, colorectal cancer (CRC) caused around 935,173 deaths worldwide in 2020
in both sexes and at all ages. The available anticancer therapies including chemotherapy …

During the past two decades, aggregation-induced emission luminogens (AIEgens) have
been intensively exploited for biological and biomedical applications. Although a series of …

Targeted delivery of anticancer drugs to cancer cells and tissues is a promising field due to
its potential to spare unaffected cells and tissues, but it has been a major challenge to …

With the advent of targeted therapies directed towards folate receptor alpha, with several
such agents in late stage clinical development, the sensitive and robust detection of folate …

Colorectal cancer (CRC) is highly prevalent worldwide, and despite notable progress in
treatment still leads to significant morbidity and mortality. The use of nanoparticles as a drug …

Tumor hypoxia is correlated with increased resistance to chemotherapy and poor overall
prognoses across a number of cancer types. We present here a cancer cell-selective and …