Depression and anxiety in Parkinson's disease

A Schrag, RN Taddei - International review of neurobiology, 2017 - Elsevier
Depression and anxiety are some of the most common comorbidities arising in patients with
Parkinson's disease. However, their timely recognition and diagnosis are often hindered by …

Distinguishing apathy from depression: A review differentiating the behavioral, neuroanatomic, and treatment‐related aspects of apathy from depression in …

KL Lanctôt, Z Ismail, KK Bawa… - … journal of geriatric …, 2023 - Wiley Online Library
Objectives This narrative review describes the clinical features of apathy and depression in
individuals with neurocognitive disorders (NCDs), with the goal of differentiating the two …

Psychosis in Parkinson's disease: epidemiology, pathophysiology, and management

A Chang, SH Fox - Drugs, 2016 - Springer
Psychotic symptoms are common in Parkinson's disease (PD) and are associated with
poorer quality of life and increased caregiver burden. PD psychosis is correlated with …

Diagnosis, treatment and management of apathy in Parkinson's disease: a scoping review

B Mele, S Van, J Holroyd-Leduc, Z Ismail… - BMJ open, 2020 - bmjopen.bmj.com
Objective To conduct a scoping review of the literature on apathy in Parkinson's disease
(PD), to better understand how apathy in Parkinson's disease is diagnosed, treated and …

Risk factors for early psychosis in PD: insights from the Parkinson's progression markers initiative

JB Pereira, C Ballard, KR Chaudhuri… - Journal of Neurology …, 2017 - jnnp.bmj.com
Background Parkinson's Disease (PD) psychosis refers to the spectrum of illusions, formed
hallucinations and delusions that occur in PD. Visual hallucinations and illusions are …

Advanced brain ageing in Parkinson's disease is related to disease duration and individual impairment

CR Eickhoff, F Hoffstaedter, J Caspers… - Brain …, 2021 - academic.oup.com
Abstract Machine learning can reliably predict individual age from MRI data, revealing that
patients with neurodegenerative disorders show an elevated biological age. A surprising …

Metabotropic glutamate receptors as therapeutic targets in Parkinson's disease: an update from the last 5 years of research

N Litim, M Morissette, T Di Paolo - Neuropharmacology, 2017 - Elsevier
Disturbance of glutamate neurotransmission in Parkinson's disease (PD) and l-DOPA
induced dyskinesia (LID) is well documented. This review focuses on advances during the …

Treatment for cognitive and neuropsychiatric non-motor symptoms in Parkinson's disease: current evidence and future perspectives

E Mantovani, C Zucchella, AA Argyriou… - Expert Review of …, 2023 - Taylor & Francis
Introduction Non-motor symptoms (NMS) affect patients with Parkinson's disease (PD) from
the prodromal to the advanced stages. NMS phenotypes greatly vary and have a huge …

Clock speed as a window into dopaminergic control of emotion and time perception

RK Cheng, J Tipples, NS Narayanan… - Timing & Time Perception, 2016 - brill.com
Although fear-producing treatments (eg, electric shock) and pleasure-inducing treatments
(eg, methamphetamine) have different emotional valences, they both produce physiological …

[HTML][HTML] A new approach for cancer prediction based on deep neural learning

H Elwahsh, MA Tawfeek, AA Abd El-Aziz… - Journal of King Saud …, 2023 - Elsevier
We know today that numerous factors play a significant role as causes of cancer. Because of
this, a doctor's opinion alone cannot be used to classify cancer. Intelligent algorithms …