Background: Some evidence suggests that antidepressants may relate to poor outcomes in
depression. The aim of this study was, therefore, to examine, whether antidepressant use …

Question We examined the effect of study characteristics, risk of bias and publication bias on
the efficacy of pharmacotherapy in randomised controlled trials (RCTs) for obsessive …

Background Clinical trials are an important source of adverse effects data, including
analyses in systematic reviews and recommendations in therapy guidelines. Trial …

Резюме В обзоре литературы рассматриваются метаанализы, систематические
обзоры и оригинальные исследования за последнее десятилетие, посвященные …

The optimal duration of antidepressant treatment for patients with major depressive disorder
to reduce the risk of relapse after discontinuation remains uncertain. Medline, Cochrane …

The diagnosis of major depressive disorder (MDD) in US youth is increasing as is the rate of
antidepressant medication (ADM) treatment for the disorder. Fluoxetine and escitalopram …

Several international guidelines for the acute treatment of moderate to severe unipolar
depression recommend a first-line treatment with antidepressants (AD). This is based on the …

RESUMO Os Problemas de Saúde Mental (SM) e o uso indiscriminado de psicofármacos
são problemas de grande relevância para a Atenção Primária à Saúde (APS) e a saúde …

Zusammenfassung Hintergrund: Zahlreiche Doppelblindstudien (randomized controlled
trials, RCTs) und Metaanalysen verweisen auf die Wirksamkeit von Antidepressiva (AD) …

Mental Health (MH) issues and the indiscriminate use of psychotropic drugs are a great deal
of a problem for the Primary Health Care (PHC) and public health. The aim of this article is to …