Scientific debate instead of beef; challenging misleading arguments about the efficacy of antidepressants

MP Hengartner - Acta neuropsychiatrica, 2019 - cambridge.org
In a recent commentary with the polemic title 'Antidepressants; what's the beef?', Goodwin
and Nutt argued that the benefit-risk ratio of antidepressants had been questioned …

Associations between pharmacological treatment patterns during the initial treatment period and the relapse or recurrence of anxiety disorders: A Nationwide …

J Kim, C Han, MS Lee, HG Jeong, JJ Kim, SH Kim - Life, 2023 - mdpi.com
Although the importance of proper pharmacological treatment for preventing the
relapse/recurrence of anxiety disorders is well known, a real-world data-based study has not …

Investigation of Hypothalamic Pituitary Adrenal Axis and Oxytocinergic System Changes in a Pragmatic Randomized Controlled Feasibility Trial of Acupuncture for …

SM Ormsby, HG Dahlen, CA Smith - Journal of Integrative and …, 2024 - liebertpub.com
Background: Antenatal depression is common and associated with detrimental impacts on
women and their families. Disrupted neuroendocrine functioning is reported in women …

What is the threshold for a clinical minimally important drug effect?

MP Hengartner - BMJ Evidence-Based Medicine, 2018 - ebm.bmj.com
Conclusions A drug is hardly effective when its average treatment effect of approximately 2
points on a subjective symptom rating scale ranging up to 52 points falls that short of a …

[PDF][PDF] False beliefs in academic psychiatry: the case of antidepressant drugs

MP Hengartner, M Plöderl - Ethical Hum Psychol Psychiatry, 2018 - researchgate.net
Antidepressant drugs are the mainstay of depression treatment in both primary and
specialized mental health care. However, academic psychiatry holds false beliefs about …

Физическая нагрузка при лечении депрессии. Режимы и виды нагрузки

ВВ Гультяева, МИ Зинченко, ДЮ Урюмцев… - Журнал неврологии и …, 2019 - elibrary.ru
При депрессии повышен риск метаболических нарушений, включая диабет 2-го типа, и
сердечно-сосудистых заболеваний, отмечается снижение продолжительности жизни …

Should we, can we, halt the rise in prescribing for pain and distress?

R Byng - British Journal of General Practice, 2020 - bjgp.org
Awareness of prescribed opioid dependence is now reaching the general population along
with concerns about levels of antidepressant prescribing and the potential for withdrawal …

[PDF][PDF] Stakeholder position statement on the NICE guideline for depression in adults

F Rost, S McPherson - 2019 - oro.open.ac.uk
Background According to the Mental Health Foundation, four in ten adults report
experiencing depression at some time in their life. The sheer scale of depression in England …

Raising placebo efficacy in antidepressant trials across decades explained by small-study effects: a meta-reanalysis

L Holper - Frontiers in psychiatry, 2020 - frontiersin.org
Background Recent meta-analyses reported placebo response rate in antidepressant trials
to be stable since the 1970s. These meta-analyses however were limited in considering only …

Suicide risk with selective serotonin reuptake inhibitors and new-generation serotonergic-noradrenergic antidepressants in adults: a systematic review and meta …

MP Hengartner, S Amendola, JA Kaminski, S Kindler… - medRxiv, 2020 - medrxiv.org
Background There is ongoing controversy whether antidepressant use alters the suicide risk
in adult routine-care patients with depression and other treatment indications. The aim of this …