Frequency, morbidity and equity—the case for increased research on male fertility

S Kimmins, RA Anderson, CLR Barratt… - Nature Reviews …, 2024 - nature.com
Currently, most men with infertility cannot be given an aetiology, which reflects a lack of
knowledge around gamete production and how it is affected by genetics and the …

The anatomy, movement, and functions of human sperm tail: an evolving mystery

N Kumar, AK Singh - Biology of reproduction, 2021 - academic.oup.com
Sperms have attracted attention of many researchers since it was discovered by Antonie van
Leeuwenhoek in 1677. Though a small cell, its every part has complex structure and …

[HTML][HTML] New insight on the in vitro effects of melatonin in preserving human sperm quality

S Minucci, M Venditti - International Journal of Molecular Sciences, 2022 - mdpi.com
Spermatozoa (SPZ) are sensitive to stressful conditions, particularly oxidative stress, which
alters their quality; thus, the use of protective molecules as an antioxidant is encouraged …

[HTML][HTML] Loss of profilin3 impairs spermiogenesis by affecting acrosome biogenesis, autophagy, manchette development and mitochondrial organization

N Umer, L Arévalo, S Phadke, K Lohanadan… - Frontiers in cell and …, 2021 - frontiersin.org
Profilins (PFNs) are key regulatory proteins for the actin polymerization in cells and are
encoded in mouse and humans by four Pfn genes. PFNs are involved in cell mobility, cell …

[HTML][HTML] Exploring the ovine sperm transcriptome by RNAseq techniques. I Effect of seasonal conditions on transcripts abundance

I Ureña, C González, M Ramón, M Gòdia, A Clop… - PLoS …, 2022 - journals.plos.org
Understanding the cell molecular changes occurring as a results of climatic circumstances is
crucial in the current days in which climate change and global warming are one of the most …

Plasmodium microtubule-binding protein EB1 is critical for partitioning of nuclei in male gametogenesis

S Mauer, N Camargo, BA Abatiyow, OR Gargaro… - Mbio, 2023 - Am Soc Microbiol
Sexual reproduction of the malaria parasites is critical for their transmission to a mosquito
vector. Several signaling molecules, such as kinases and phosphatases, are known to …

Taurine and its transporter TAUT positively affect male reproduction and early embryo development

H Wu, X Zhang, J Yang, T Feng, Y Chen… - Human …, 2022 - academic.oup.com
STUDY QUESTION Are taurine and its transporter TAUT associated with spermiogenesis
and early embryo development? SUMMARY ANSWER Morphologically abnormal …

DAAM1 and PREP are involved in human spermatogenesis

M Venditti, C Fasano, S Minucci, I Serino… - Reproduction …, 2020 - CSIRO Publishing
During differentiation of the male gamete, there is a massive remodelling in the shape and
architecture of all the cells in the seminiferous epithelium. The cytoskeleton, as well as many …

[HTML][HTML] A comprehensive genetic study of microtubule-associated gene clusters for male infertility in a Taiwanese cohort

CC Chan, TH Yen, HC Tseng, B Mai, PK Ho… - International Journal of …, 2023 - mdpi.com
Advanced reproductive technologies are utilized to identify the genetic mutations that lead to
spermatogenic impairment, and allow informed genetic counseling to patients to prevent the …

Fuel/energy sources of spermatozoa

P Sengupta, D Durairajanayagam… - … , Andrology, ART and …, 2020 - Springer
Spermatozoa consume energy in the form of intracellular adenosine triphosphate (ATP)
generated by its fuel machinery. Energy is required to facilitate sperm functions, from sperm …