The Epidemiology and Pathogenesis and Treatment of Pseudomonas aeruginosa Infections: An Update

D Reynolds, M Kollef - Drugs, 2021 - Springer
Pseudomonas aeruginosa is a Gram-negative bacterial pathogen that is a common cause of
nosocomial infections, particularly pneumonia, infection in immunocompromised hosts, and …

Biofilm dispersion

KP Rumbaugh, K Sauer - Nature Reviews Microbiology, 2020 - nature.com
The formation of microbial biofilms enables single planktonic cells to assume a multicellular
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …

[HTML][HTML] Biofilm patterns in gram-positive and gram-negative bacteria

R Ruhal, R Kataria - Microbiological Research, 2021 - Elsevier
Abstract The Gram-positive and Gram-negative bacteria are attributable to matrix-enclosed
aggregates known as biofilms. Biofilms are root cause of industrial biofouling and …

Cystic fibrosis and Pseudomonas aeruginosa: the host-microbe interface

S Malhotra, D Hayes Jr, DJ Wozniak - Clinical microbiology …, 2019 - Am Soc Microbiol
In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria

XZ Li, P Plésiat, H Nikaido - Clinical microbiology reviews, 2015 - Am Soc Microbiol
The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …

Lipopolysaccharide modification in Gram-negative bacteria during chronic infection

RF Maldonado, I Sá-Correia… - FEMS microbiology …, 2016 - academic.oup.com
The Gram-negative bacterial lipopolysaccharide (LPS) is a major component of the outer
membrane that plays a key role in host–pathogen interactions with the innate immune …

Cystic fibrosis lung environment and Pseudomonas aeruginosa infection

AY Bhagirath, Y Li, D Somayajula, M Dadashi… - BMC pulmonary …, 2016 - Springer
Background The airways of patients with cystic fibrosis (CF) are highly complex, subject to
various environmental conditions as well as a distinct microbiota. Pseudomonas aeruginosa …

Epidemiology, biology, and impact of clonal Pseudomonas aeruginosa infections in cystic fibrosis

MD Parkins, R Somayaji, VJ Waters - Clinical microbiology …, 2018 - Am Soc Microbiol
Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …

First contact: the role of respiratory cilia in host-pathogen interactions in the airways

LE Kuek, RJ Lee - … Journal of Physiology-Lung Cellular and …, 2020 - journals.physiology.org
Respiratory cilia are the driving force of the mucociliary escalator, working in conjunction
with secreted airway mucus to clear inhaled debris and pathogens from the conducting …

Molecular signatures and phylogenomic analysis of the genus Burkholderia: proposal for division of this genus into the emended genus Burkholderia containing pathogenic …

A Sawana, M Adeolu, RS Gupta - Frontiers in genetics, 2014 - frontiersin.org
The genus Burkholderia contains large number of diverse species which include many
clinically important organisms, phytopathogens, as well as environmental species. However …