Learning and memory are two of the most magical capabilities of our mind. Learning is the
biological process of acquiring new knowledge about the world, and memory is the process …

Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

The analysis of the contributions to synaptic plasticity and memory of cAMP, PKA, CRE,
CREB-1, CREB-2, and CPEB has recruited the efforts of many laboratories all over the …

Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …

Many neurological and most psychiatric disorders are not due to mutations in a single gene;
rather, they involve molecular disturbances entailing multiple genes and signals that control …

In adult hippocampus, new neurons are continuously generated from neural stem cells
(NSCs), but the molecular mechanisms regulating adult neurogenesis remain elusive. We …

Micro-electrode arrays (MEAs) are increasingly used to characterize neuronal network
activity of human induced pluripotent stem cell (hiPSC)-derived neurons. Despite their gain …

Mammalian neural stem cells (NSCs) have the capacity to both self-renew and to generate
all the neuronal and glial cell-types of the adult nervous system. Global chromatin changes …

Oligodendrocyte development is regulated by the interaction of repressors and activators in
a complex transcriptional network. We found that two histone-modifying enzymes, HDAC1 …

Precise regulation of transcription is crucial for the cellular mechanisms underlying memory
formation. However, the link between neuronal stimulation and the proteins that directly …