Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …

Growing evidence suggests that the physical properties of the cellular microenvironment
influence cell migration. However, it is not currently understood how active physical …

Collective cell migration on extracellular matrix (ECM) networks is a key biological process
involved in development, tissue homeostasis and diseases such as metastatic cancer …

Significant changes in cell stiffness, contractility, and adhesion, ie, mechanotype, are
observed during a variety of biological processes. Whether cell mechanics merely change …

Cell migration is crucial for organismal development and shapes organisms in health and
disease. Although a lot of research has revealed the role of intracellular components and …

Directed cell migration towards a softer environment is called negative durotaxis. The
mechanism and pathological relevance of negative durotaxis in tumor progression still …

细胞膜是细胞与外部环境进行物质与能量交换的界面, 是调节细胞正常生命活动的重要结构基础
. 细胞膜上力敏感受体可通过力学作用方式参与并影响细胞的力信号转导等功能 …

Cell migration is essential for a variety of biological processes, such as embryogenesis,
wound healing, and the immune response. After more than a century of research—mainly on …

Cell migration is oriented by cues from the environment. Such cues are read and interpreted
by the cell and translated into a reorganization of the migration machinery to steer migration …

Increasing experimental evidence validates that both the elastic stiffness and viscosity of the
extracellular matrix regulate mesenchymal cell behavior, such as the rational switch …