CXCL1: Gene, Promoter, Regulation of Expression, mRNA Stability, Regulation of Activity in the Intercellular Space

J Korbecki, K Barczak, I Gutowska, D Chlubek… - International journal of …, 2022 - mdpi.com
CXCL1 is one of the most important chemokines, part of a group of chemotactic cytokines
involved in the development of many inflammatory diseases. It activates CXCR2 and, at high …

African Plasmodium vivax malaria improbably rare or benign

JK Baird - Trends in Parasitology, 2022 - cell.com
The overwhelming dominance of Duffy blood group negativity among most people living in
sub-Saharan Africa has been considered the basis of their protection from endemic …

Prevalence and risk of Plasmodium vivax infection among Duffy-negative individuals: a systematic review and meta-analysis

P Wilairatana, FR Masangkay, KU Kotepui… - Scientific Reports, 2022 - nature.com
A better understanding of the occurrence and risk of Plasmodium vivax infection among
Duffy-negative individuals is required to guide further research on these infections across …

The biology of unconventional invasion of Duffy-negative reticulocytes by Plasmodium vivax and its implication in malaria epidemiology and public health

L Golassa, L Amenga-Etego, E Lo, A Amambua-Ngwa - Malaria journal, 2020 - Springer
Plasmodium vivax has been largely neglected over the past century, despite a widespread
recognition of its burden across region where it is endemic. The parasite invades …

The enigmatic mechanisms by which Plasmodium vivax infects Duffy-negative individuals

J Popovici, C Roesch, V Rougeron - PLoS Pathogens, 2020 - journals.plos.org
The absence of the Duffy protein at the surface of erythrocytes was considered for decades
to confer full protection against Plasmodium vivax as this blood group is the receptor for the …

Vivax malaria in Duffy-negative patients shows invariably low asexual parasitaemia: implication towards malaria control in Ethiopia

A Abate, I Bouyssou, S Mabilotte, C Doderer-Lang… - Malaria Journal, 2022 - Springer
Background The increase in detections of Plasmodium vivax infection in Duffy-negative
individuals in Africa has challenged the dogma establishing the unique P. vivax Duffy …

A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related …

SE Legge, AF Pardiñas, M Helthuis, JA Jansen… - Molecular …, 2019 - nature.com
Individuals of African ancestry in the United States and Europe are at increased risk of
developing schizophrenia and have poorer clinical outcomes. The antipsychotic clozapine …

The Black Box of Cellular and Molecular Events of Plasmodium vivax Merozoite Invasion into Reticulocytes

J Molina-Franky, C Reyes, YA Picón Jaimes… - International Journal of …, 2022 - mdpi.com
Plasmodium vivax is the most widely distributed malaria parasite affecting humans
worldwide, causing~ 5 million cases yearly. Despite the disease's extensive burden, there …

How to choose sets of ancestry informative markers: A supervised feature selection approach

P Pfaffelhuber, F Grundner-Culemann… - Forensic Science …, 2020 - Elsevier
Abstract Inference of the Biogeographical Ancestry (BGA) of a person or trace relies on three
ingredients:(1) a reference database of DNA samples including BGA information;(2) a …

Extended phenotyping does not preclude the occurrence of delayed haemolytic transfusion reactions in sickle cell disease

J Gerritsma, V Bongaerts, C Eckhardt… - British Journal of …, 2022 - Wiley Online Library
Delayed haemolytic transfusion reaction (DHTR) is a potentially life‐threatening
complication of red blood cell (RBC) transfusions in sickle cell disease (SCD) and is …