Semaphorin regulation by the chromatin remodeler chd7: An emerging genetic interaction shaping neural cells and neural crest in development and cancer

A Lettieri, R Oleari, AJJ Paganoni… - Frontiers in Cell and …, 2021 - frontiersin.org
CHD7 is a chromatin remodeler protein that controls gene expression via the formation of
multi-protein complexes with specific transcription factors. During development, CHD7 …

Semaphorin 6C suppresses proliferation of pancreatic cancer cells via inhibition of the AKT/GSK3/β-catenin/cyclin D1 pathway

YH Hung, SH Hsu, YC Hou, PY Chu, YY Su… - International journal of …, 2022 - mdpi.com
Semaphorins (SEMAs) are axon guidance factors that participate in axonal connections and
nerve system development. However, the functional roles of SEMAs in tumorigenesis are …

Mechanochemical control of epidermal stem cell divisions by B-plexins

C Jiang, A Javed, L Kaiser, MM Nava, R Xu… - Nature …, 2021 - nature.com
The precise spatiotemporal control of cell proliferation is key to the morphogenesis of
epithelial tissues. Epithelial cell divisions lead to tissue crowding and local changes in force …

The role of Semaphorin 3A in oral diseases

X Zhang, Z Yang, D Zhang, M Bai - Oral Diseases, 2024 - Wiley Online Library
Abstract Semaphorin 3A (SEMA3A), also referred to as H‐Sema III, is a molecule with
significant biological importance in regulating physiological and pathological processes …

Semaphorin 3A—glycosaminoglycans interaction as therapeutic target for axonal regeneration

Y Pérez, R Bonet, M Corredor, C Domingo, A Moure… - Pharmaceuticals, 2021 - mdpi.com
Semaphorin 3A (Sema3A) is a cell-secreted protein that participates in the axonal guidance
pathways. Sema3A acts as a canonical repulsive axon guidance molecule, inhibiting CNS …

[HTML][HTML] Molecular Analysis of Murine KitK641E Melanoma Progression

E Everdell, Z Ji, CN Njauw, H Tsao - JID Innovations, 2024 - Elsevier
Acral and mucosal melanomas are often driven by sequence variants in the KIT receptor
tyrosine kinase, with nearly 40% harboring alterations in the KIT locus. Despite advances in …

A cell surface code mediates tissue-intrinsic defense against aberrant cells in epithelia

F Fischer, L Ernst, A Frey, K Holstein, D Prasad… - bioRxiv, 2023 - biorxiv.org
Tissue-intrinsic error-correction mechanisms allow epithelial cells to detect aberrant
neighboring cells and cause their removal from the tissue. The molecular mechanisms …

Biophysical Reviews: a Q1 ranked journal in biophysics and structural biology

D Hall - Biophysical reviews, 2020 - Springer
Abstract This Editorial for Biophysical Reviews (Volume 12, Issue 5) begins with a
description of the two feature articles. The first being the latest in the “Meet the Editors …

A mismatch in the expression of cell surface molecules induces tissue-intrinsic defense against aberrant cells

F Fischer, L Ernst, A Frey, K Holstein, D Prasad… - Current Biology, 2024 - cell.com
Tissue-intrinsic error correction enables epithelial cells to detect abnormal neighboring cells
and facilitate their removal from the tissue. One of these pathways," interface surveillance," is …

[引用][C] Impact on properties of biophysical environment

P Shang - Allied J Med Res. 2022; 6 (9)